Summary
Stereoselective oxidation of (S)-isomer of rac-1-phenylethanol (1-PA) by the yeast Pachysolen tannophilus IFO 1007 immobilized into calcium-alginate gels was investigated to produce (R)-isomer. Continuous production of (R)-isomer was accomplished for more than 80 h with an enantiomeric excess of > 90% using a bioreactor of a fluidized-bed type.
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Hasegawa, Y., Uosaki, H., Adachi, S. et al. Production of (R)-1-phenylethanol through enantioselective oxidation of (S)-isomer from their racemic mixture by Pachysolen tannophilus IFO 1007. Biotechnol Lett 18, 367–372 (1996). https://doi.org/10.1007/BF00143453
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DOI: https://doi.org/10.1007/BF00143453