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Changes in macular function throughout adulthood

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Abstract

Recent reports suggest that the neural system is the principal cause of loss of visual function with age and that senile lenticular and pupillary changes are of minor importance. In order to investigate this neural deterioration further we measured Logmar visual acuity and photostress recovery time (PSRT) in 61 subjects over an age range of 19 to 78 years. The magnitude of the PSRT reflects the efficiency with which the visual system recovers from exposure to a glare source and is principally dependent upon the integrity of the photoreceptors and the retinal pigment epithelium. The results indicate that macular function declines significantly throughout adulthood.

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References

  1. Weale, RA. Senile changes in visual acuity. Trans Ophthalmol Soc UK 1975; 95: 36–38.

    Google Scholar 

  2. Jay, JL, Mammo, RB, Allan, D. Effect of age on visual acuity after cataract extraction. Br J Ophthalmol 1987; 71: 112–15.

    Google Scholar 

  3. Morrison, JD, McGrath, C. Assessment of the optical contributions to the age-related deterioration in vision. QJ Exp Physiol 1985; 70: 249–69.

    Google Scholar 

  4. Owsley, C, Gardner, T, Sekuler, R, Lieberman, H. Role of the crystalline lens in the spatial vision loss of the elderly. Invest Ophthalmol Vis Sci 1985; 26: 1165–70.

    Google Scholar 

  5. Elliott, DB. Contrast sensitivity decline with ageing: a neural or optical phenomenon? Ophthal Physiol Opt 1987; 7: 415–19.

    Google Scholar 

  6. Sloane, ME, Owsley, C, Jackson, CA. Aging and luminance-adaptation effects on spatial contrast sensitivity. J Opt Soc Am 1988; A5: 2181–90.

    Google Scholar 

  7. Elliott, DB, Whitaker, D, MacVeigh, D. Neural contribution to spatiotemporal contrast sensitivity decline in healthy ageing eyes. Vision Res 1990; 30: 541–47.

    Google Scholar 

  8. Johnson, CA, Adams, AJ, Lewis, RA. Evidence for a neural basis of age-related visual field loss in normal observers. Invest Opthalmol Vis Sci 1989; 30: 2056–64.

    Google Scholar 

  9. Elliott, DB, Whitaker, D, Thompson, P. Use of displacement threshold hyperacuity to isolate the neural component of senile vision loss. Appl Opt 1989; 28: 1914–18.

    Google Scholar 

  10. Weale, RA. Do years or quanta age the retina? Photochemistry and Photobiology 1989; 50: 429–38.

    Google Scholar 

  11. Wing, GL, Blanchard, GC, Weiter, JJ. The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium. Invest Ophthalmol Vis Sci 1978; 17: 601–07.

    Google Scholar 

  12. Weale, RA. The eye and ageing. Interdiscipl Topics Gerontol 1978; 13: 1–13.

    Google Scholar 

  13. Gartner, S, Henkind, P. Ageing and degeneration of the human macula, 1: Outer nuclear layer and photoreceptors. Br J Ophthalmol 1981; 65: 23–8.

    Google Scholar 

  14. Ordy, JM, Brizee, KR, Johnson, HA. Cellular alterations in visual pathways and the limbic system: Implications for vision and short term memory. In: Sekuler, R, Kline, D, Dismukes, K(eds), Aging and Human Visual Function. New York: Liss, 1982: 79–114.

    Google Scholar 

  15. Sekuler, R, Kline, D, Dismukes, K, Adams, AJ. Some research needs in aging and visual preception. Vision Res 1983; 23: 213–16.

    Google Scholar 

  16. Brindley, GS. The discrimination of after-images. J Physiol 1959; 147: 194–203.

    Google Scholar 

  17. Severin, SL, Tour, RL, Kershaw, RH. Macular function and the photostress test. Arch Ophthalmol 1967; 77: 2–7.

    Google Scholar 

  18. Glaser, JS, Savino, PJ, Sumers, KD, McDonald, SA, Knighton, RW. The photostress recovery test in the clinical assessment of visual function. Am J Ophthalmol 1977; 83: 255–60.

    Google Scholar 

  19. Lovasik, JV. An elecrophysiological investigation of the macular photostress test. Invest Ophthalmol Vis Sci 1983; 24: 437–41.

    Google Scholar 

  20. Collins, M, Brown, B. Glare recovery and age-related maculopathy. Clin Vis Sci 1989; 4: 145–53.

    Google Scholar 

  21. Collins, M. The onset of prolonged glare recovery with age. Ophthal Physiol Opt 1989; 9: 368–71.

    Google Scholar 

  22. Weale, RA. Retinal illumination and age. Trans Illum Eng Soc 1961; 26: 95–9.

    Google Scholar 

  23. Higgins, KE, Jaffe, MJ, Caruso, RC, de Monasterio, FM. Spatial contrast sensitivity: effects of age, test-retest, and psychophysical method. J Opt Soc Am 1988; A5: 2173–80.

    Google Scholar 

  24. Ferris, FL, Kassof, A, Bresnick, GH, Bailey, I. New visual acutiy charts for clinical research. Am J Ophthalmol 1982; 94: 91–6.

    Google Scholar 

  25. Westheimer, G. Scaling of visual acuity measurements. Arch Ophthalmol 1979; 97: 327–30.

    Google Scholar 

  26. Elliott, DB, Sheridan, M. The use of accurate visual acuity measurements in clinical anti-cataract formulation trails. Ophthal Physiol Opt 1988; 8: 397–401.

    Google Scholar 

  27. Weale, RA. A Biography of the Eye. London: HK Lewis and Co, 1982.

    Google Scholar 

  28. Elsner, AE, Berk, L, Burns, SA, Rosenberg, PR. Aging and human cone photopigments. J Opt Soc Am 1988; A5: 2106–112.

    Google Scholar 

  29. Keunen, JEE, van Norren, D, van Meel, GJ. Density of foveal cone pigments at older age. Invest Ophthalmol Vis Sci 1987; 28: 985–91.

    Google Scholar 

  30. Kilbride, PE, Hutman, LP, Fishman, M, Read, JS. Foveal cone pigment density difference in the aging human eye. Vision Res 1986; 26: 321–25.

    Google Scholar 

  31. Knoblauch, K, Saunders, F, Kusuda, M, Hynes, R, Podgor, M, Higgins, KE, De Monasterio, FM. Age and illuminance effects in the Farnsworth-Munsell 100-hue test. Appl Opt 1987; 26: 1441–8.

    Google Scholar 

  32. Werner, JS, Steel, VG. Sensitivity of human foveal colour mechanisms throughout the life span. J Opt Soc Am 1988; A5: 2122–30.

    Google Scholar 

  33. Birch, DG, Fish, GE. Focal cone electroretinograms: Aging and macular disease. Doc Ophthalmol 1988; 69: 211–6.

    Google Scholar 

  34. Tulunay-Keesey, U, ver Hoeve, JN, Terkla-McGrane, C. Threshold and suprathreshold spatiotemporal response throughout adulthood. J Opt Soc Am 1988; A5: 2191–200.

    Google Scholar 

  35. Collier, RJ, Waldron, WR, Zigman, S. Temporal sequence of changes to the gray squirrel retina after near-UV exposure. Invest Ophthalmol Vis Sci 1989; 30: 631–7.

    Google Scholar 

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Elliott, D.B., Whitaker, D. Changes in macular function throughout adulthood. Doc Ophthalmol 76, 251–259 (1990). https://doi.org/10.1007/BF00142684

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