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The relationship between sporulation and solvent production in clostridium acetobutylicum P262

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Summary

Single and multiple Clostridium acetobutylicum P262 sporulation, clostridial stage, granulose, capsule and solvent producing mutants were isolated. Although common regulatory components were involved in the regulation of these events, each individual pathway was able to function independently of each other. Inhibitors of DNA replication inhibited spore formation but did not affect solvent, clostridial stage, granulose and capsule production.

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References

  • Barber, J.M., Robb, F.T., Webster, J.R., and Woods, D.R. (1979). Appl. Environ. Micrbiol.37, 433–437.

    Google Scholar 

  • Bu'Lock, J.D., and Bu'Lock, A.J. (1983). The acetone-butanol fermentation and related topics 1980–1983. Science and Technology Letters, Kew, England.

  • Burke, W.F., and Spizizen, J. (1977). J. Bacteriol.129, 1215–1221.

    Google Scholar 

  • Dunn, G., Jeffs, P., Mann, N.H., Togersen, D.M., and Young, M. (1978). J. Gen. Microbiol.108, 189–195.

    Google Scholar 

  • Gottschal, J.C., and Morris, J.G. (1981). Biotechnol. Lett.3, 525–530.

    Google Scholar 

  • Hoeniger, J.F.M., and Headley, C.L. (1968). J. Bacteriol.96, 1835–1847.

    Google Scholar 

  • Jones, D.T., van der Westhuizen, A., Long, S., Allcock, E.R., Reid, S.J., and Woods, D.R. (1982). Appl. Environ. Microbiol.43, 1434–1439.

    Google Scholar 

  • Long, S., Jones, D.T., and Woods, D.R. (1983). Appl. Environ. Microbiol.45, 1389–1393.

    Google Scholar 

  • Long, S., Jones, D.T., and Woods, D.R. (1984). European J. Appl. Microbiol. Biotechnol. In press.

  • Mackey, B.M., and Morris, J.G. (1971). J. Gen. Microbiol.66, 1–13.

    Google Scholar 

  • Mandelstam, J., and Higgs, S.A. (1974). J. Bacteriol.120, 38–42.

    Google Scholar 

  • O'Brien, R.W., and Morris, J.G. (1971). J. Gen. Microbiol.68, 307–318.

    Google Scholar 

  • Prescott, S.C., and Dunn, C.G. (1959). Industrial Microbiology, 3rd ed. McGraw-Hill Book Co., New York.

    Google Scholar 

  • Rogolsky, M., and Nakamura, H.T. (1974). J. Bacteriol.119, 57–61.

    Google Scholar 

  • Smith, A.G., and Ellner, P.D. (1957). J. Bacteriol.73, 1–7.

    Google Scholar 

  • Takahashi, I., and Mackenzie, L.W. (1982). Can. J. Microbiol.28, 80–86.

    Google Scholar 

  • Vasques-Ramos, J.M., and Mandelstam, J. (1981). J. Gen. Microbiol.127, 11–17.

    Google Scholar 

  • Young, M., and Mandelstam, J. (1979). Adv. Microb. Physiol.20, 102–162.

    Google Scholar 

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Long, S., Jones, D.T. & Woods, D.R. The relationship between sporulation and solvent production in clostridium acetobutylicum P262. Biotechnol Lett 6, 529–534 (1984). https://doi.org/10.1007/BF00139997

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