Summary
Two patients with orbital metastasis from cutaneous melanoma are described. In one patient the metastatic tumour was located in the iris, in the other one it was located in the lateral rectus muscle. Only symptomatic treatment is indicated as the term of survival is short.
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References
Gupta TD, Brasfield R: Metastatic melanoma. Cancer 17: 1323–1339, 1964
Font RL, Naumann G, Zimmerman LE: Primary malignant melanoma of the skin metastatic to the eye and orbit. Report of ten cases and review of the literature. Am J Ophthalmol 63: 738–754, 1967
Letson AD, Davidorf FH: Bilateral retinal metastases from cutaneous malignant melanoma. Arch Ophthalmol 100: 605–607, 1982
Char DH, Schwartz A, Miller TR, Abele JS: Ocular metastases from systemic melanoma. Am J Ophthalmol 90: 702–707, 1980
Cole EL, Zakov ZN, Meisler DM, Tuthill RJ, McMahon JT: Cutaneous malignant melanoma metastatic to the vitreous. Arch Ophthalmol 104: 98–101, 1986
De Keizer RJW, Vielvoye GJ, De Wolff-Rouendaal D: Nuclear magnetic resonance imaging of intraocular tumors. Am J Ophthalmol 102: 438–441, 1986
Lynch HT, Fusaro RM, Pester J, Oosterhuis JA, Went LN, Rumke P, Neering H, Lynch JF: Tumour spectrum in the FAMMM syndrome. Br J Cancer 44: 553–560, 1981
Oosterhuis JA, Went LN, Lynch HT: Primary choroidal and cutaneous melanomas, bilateral choroidal melanomas, and familial occurrence of melanomas. Br J Ophthalmol 66: 230–233, 1982
Cutler SJ, Young JL: Third National Cancer Survey: Incidence Data. National Cancer Institute Monograph No. 41. US Government Printing Office, 1975
Paton D, Thomas LB: Simultaneous occurrence of primary malignant melanomas of the eye and the skin. Arch Ophthalmol 62: 645–652, 1959
Augsburger JJ, Shields JA, Frank PE, Mastrangelo MJ: Diffuse primary malignant melanoma after prior primary cutaneous malignant melanoma. Arch Ophthalmol 98: 1261–1264, 1980
Wagenmann D: Ein Fall von multiplen Melanosarkomen mit eigenartigen Komplikationen beider Augen. Deutsch Med Wschr 25: 262, 1900
Adamük: Ein Fall von metastatischem Melanosarkom der Uvea. Z Augenh 21: 505, 1909
Ten Doesschate G: Über metastatisches Sarkom des Auges. Klin Mbl Augenh 66: 766, 1921
Stark WJ, Rosenthal AR, Mullins GM, Green WR: Simultaneous bilateral uveal melanomas responding to BCNU therapy. Trans Am Acad Ophthalmol Otolaryngol 75: 70–83, 1971
Vida LO, Binder PS: Simultaneous metastasis of skin melanoma to the eye and orbit. Ann Ophthalmol 10: 431–433, 1978
Lommatzsch P, Tost M: Intraokulare Metastasen bei primären Hautmelanomen. Beobachtung von 4 Fällen. Klin Mbl Augenhk 174: 686–693, 1979
Hirst LW, Reich J, Galbraith JEK: Primary cutaneous malignant melanoma metastatic to the iris. Br J Ophthalmol 63: 165–168, 1979
De Bustros S, Augsburger JJ, Shields JA, Shakin EP, PryorII CC: Intraocular metastases from cutaneous malignant melanoma. Arch Ophthalmol 103: 937–940, 1985
Zimmerman LE: Role of the histopathologist in a uveitis program. In: Aronson, Gamble, Goodner, O'Connor (eds) Clinical methods in uveitis. Mosby Co St Louis, 1968, pp 128–135
Rockwood EJ, Zakov ZN, Bay JW: Combined malignant lymphoma of the eye and CNS (reticulum-cell sarcoma). J Neurosurg 61: 369–374, 1984
Fishman ML, Tomaszewski MM, Kuwabara T: Malignant melanoma of the skin metastatic to the eye. Frequency in autopsy series. Arch Ophthalmol 94: 1309–1311, 1976
Bedford PD, Daniel PM: Discrete carcinomatous metastases in the extrinsic ocular muscles. A case of carcinoma of the breast with exophthalmic ophthalmoplegia. Am J Ophthalmol 49: 723–726, 1960
Mortada A: Binocular diplopia due to metastasis in orbital muscle from female breast cancer years after radical mastectomy. Orbit 3: 71–74, 1984
Ferry AP: Primary malignant melanoma of the skin metastatic to the eye. Am J Ophthalmol 74: 12–19, 1972
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Oosterhuis, J.A., de Keizer, R.J.W., de Wolff-Rouendaal, D. et al. Ocular and orbital metastasis of cutaneous melanomas. Int Ophthalmol 10, 175–184 (1987). https://doi.org/10.1007/BF00139345
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DOI: https://doi.org/10.1007/BF00139345