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Dry-column chromatographic purification of aflatoxin precursors

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Abstract

The toxic and carcinogenic properties of aflatoxins are well understood, but little is known about the biological activity of the anthraquinone precursors of aflatoxin. This paper describes a dry column chromatographic method for preparing averantin, averufin, norsolorinic acid and versicolorin A from mycelial extracts of blocked mutants of Aspergillus parasiticus in quantities suitable for toxicological testing.

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Authors and Affiliations

  1. U. S. Department of Agriculture, Southern Regional Research Center, Science and Education Administration, 70179, New Orleans, Louisiana, USA

    J. J. Dunn & L. S. Lee

  2. Department of Biology, Tulane University, 70118, New Orleans, Louisiana, USA

    J. W. Bennett

Authors
  1. J. J. Dunn
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  2. L. S. Lee
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  3. J. W. Bennett
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Dunn, J.J., Lee, L.S. & Bennett, J.W. Dry-column chromatographic purification of aflatoxin precursors. Biotechnol Lett 2, 17–22 (1980). https://doi.org/10.1007/BF00136878

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  • DOI: https://doi.org/10.1007/BF00136878

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