ECA109 human oesophageal carcinoma cells were injected either subcutaneously or intraperitoneally into BALB/CATc 1-nu/nu mice. After 23 weeks tumours were examined histologically and by scanning electron microscopy. Subcutaneous ECA109 tumours were well-delineated without signs of invasion. By contrast, intra-abdominal tumours invaded into the abdominal wall and abdominal organs. This result provides us with another example of site-dependence of invasionin vivo.
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Jin, G., Kexue, X., Baogui, L. et al. Site-dependence of invasiveness of ECA109 human oesophageal carcinoma cells in nude mice. Clin Exp Metast 2, 205–212 (1984). https://doi.org/10.1007/BF00132927
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DOI: https://doi.org/10.1007/BF00132927