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Mutagenic treatment of chlortetracycline producer with acriflavine

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Summary

Acriflavine treatment of Streptomyces aureofaciens gives rise to a high proportion of mutants withloss of antibiotic production and with morphological changes. Mutants so obtained are compared with those arising after UV irradiation.

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Vyskocil, P., Zelený, K. Mutagenic treatment of chlortetracycline producer with acriflavine. Biotechnol Lett 4, 277–280 (1982). https://doi.org/10.1007/BF00132825

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  • DOI: https://doi.org/10.1007/BF00132825

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