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Asymmetric fundus flavimaculatus/Stargardt's disease, associated with unilateral myopia

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Abstract

An unusual asymmetric pattern of fundus flavimaculatus was observed in a unilateral myopic patient. Although electrophysiologic testing was similar for both eyes, fundus lesions were different and less pronounced in the myopic eye.

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References

  1. Kaplan J, Gerber S, Larget-Piet D, Rozet JM, Dollfus H, Dufier J. A gene for Stargardt's disease (fundus flavimaculatus) maps to the short arm of chromosome 1. Nat Genet 1993; 5: 308–11.

    Google Scholar 

  2. Stone EM, Nichols BE, Kimura AE, Weingeist TA, Drack A, Sheffield VC. Clinical features of a Stargardt-like dominant progressive macular dystrophy with genetic linkage to chromosome 6q. Arch Ophthalmol 1994; 112: 765–72.

    Google Scholar 

  3. Zhang K, Bither PP, Park R, Donoso LA, Seidman JG, Seidman CE. A dominant Stargardt's macular dystrophy locus maps to chromosome 13q34. Arch Ophthalmol 1994; 112: 759–64.

    Google Scholar 

  4. Weleber RG, Carr RE, Murphey WH, Sheffield VC, Stone EM. Phenotypic variation including retinitis pigmentosa, pattern dystrophy and fundus flavimaculatus in a single family with a deletion of codon 153 and 154 of the peripherin/RDS gene. Arch Ophthalmol 1993; 111: 1531–42.

    Google Scholar 

  5. Stargardt K. Ueber familiäre, progressive Degeneration in der Maculagegend des Auges. von Graefe's Arch. Clin Exp Ophthalmol 1909; 71: 534–50.

    Google Scholar 

  6. Franceschetti A. A special form of tapetoretinal degeneration: fundus flavimaculatus. Trans Am Acad Ophthalmol Otolaryngol 1965; 69: 1048–53.

    Google Scholar 

  7. Deutman AF. The heriditary dystrophies of the posterior pole of the eye. The Netherlands: Van Gorcum C∘, Assen, 1971: 100–71.

    Google Scholar 

  8. Eagle RC Jr, Lucier AD, Bernardino JB Jr, Yanoff M. Retinal pigment epithelial abnormalities in fundus flavimaculatus: a light and electron microscopic study. Ophthalmology 1980; 87: 1189–2000.

    Google Scholar 

  9. Lopez PF, Maumenee IH, de la Cruz Z, Green WR. Autosomal dominant fundus flavimaculatus. Clinicopathologic correlation. Ophthalmology 1990; 97: 798–809.

    Google Scholar 

  10. Steinmetz RL, Garner A, Maguire JI, Bird AC. Histopathology of incipient fundus flavimaculatus. Ophthalmology 1991; 98: 953–6.

    Google Scholar 

  11. Birnbach CD, Järvaläinen M, Possin DM, Milam AH. Histopathology and immunochemistry of the neurosensory retina in fundus flavimaculatus. Ophthalmology 1994; 101: 1211–9.

    Google Scholar 

  12. Bonnin P. Le signe du silence choroïdien dans les dégénérescenses tapétorétiniennes centrales examinées sous fluorescéine. Bull Soc Ophtalmol Fr 1971; 71: 348–51.

    Google Scholar 

  13. Fishman GA. Fundus flavimaculatus: a clinical classification. Arch Ophthalmol 1976; 94: 2061–7.

    Google Scholar 

  14. Gelisken O, De Laey JJ. A clinical review of Stargardt's disease and/or fundus flavimaculatus with follow-up. Int Ophthalmol 1985; 8: 225–35.

    Google Scholar 

  15. Iijima H, Gohdo T, Hosaka O. Fundus flavimaculatus with severely reduced cone electroretinogram. Jap J Ophthalmol 1992; 36: 249–56.

    Google Scholar 

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Authors and Affiliations

  1. Department of Ophthalmology, University Hospital Ghent, Ghent, Belgium

    B. A. Lafaut, J. van Egmond & J. J. De Laey

Authors
  1. B. A. Lafaut
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  2. J. van Egmond
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  3. J. J. De Laey
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Lafaut, B.A., van Egmond, J. & De Laey, J.J. Asymmetric fundus flavimaculatus/Stargardt's disease, associated with unilateral myopia. Int Ophthalmol 19, 253–255 (1995). https://doi.org/10.1007/BF00132695

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  • DOI: https://doi.org/10.1007/BF00132695

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