Summary
Extended and enhanced production of swainsonine was achieved from fed-batch fermentations of the fungus Metarhizium anisopliae. A complex medium based on oatmeal extract was intermittently fed with D-glucose and/or lysine. Swainsonine titres were improved eleven-fold and the duration of production extended was from 240 to 550 hours compared with a batch culture under the same conditions.
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Patrick, M.S., Adlard, M.W. & Keshavarz, T. Swainsonine production in fed-batch fermentations of Metarhizium anisopliae . Biotechnol Lett 17, 433–438 (1995). https://doi.org/10.1007/BF00130803
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DOI: https://doi.org/10.1007/BF00130803