Summary
Semi-pilot scale production of citric acid was investigated with a gamma-ray induced mutant (HB3) of Aspergillus niger using 500, 1000 and 1500 ml medium in 51 fermentation jars. Yield of citric acid was found to be seven-fold higher compared to the parent in 1000 ml medium and the corresponding increase was two-fold in the 500 ml medium. With 1500 ml/fermentation jar the yield was low with both the parent and the mutant strain though the mutant gave higher yield compared to the parent.
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Islam, M.S., Begum, R. & Choudhury, N. Semi-pilot scale studies on citric acid fermentation by a gamma-ray induced mutant of Aspergillus niger. Biotechnol Lett 6, 431–434 (1984). https://doi.org/10.1007/BF00129304
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DOI: https://doi.org/10.1007/BF00129304