Abstract
An unusual large heterochromatic segment around the pericentromeric region of the X-chromosome is reported. In normal circumstances, the pericentromeric region of the X-chromosome is negative by the restriction endonuclease AluI/Giemsa technique. However, this unusual X-chromosome was found to have AluI resistant (positive) chromatin. The evolution of extra heterochromatin is a postzygotic event as substantiated by the presence of a normal cell line.
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Luke, S., Mathews, T. & Verma, R.S. Evolution of pericentromeric heterochromatin of human X chromosome. Genetica 87, 63–64 (1992). https://doi.org/10.1007/BF00128774
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DOI: https://doi.org/10.1007/BF00128774