Abstract
Fifty vitreous specimens obtained by routine pars plana vitrectomies were examined using Millipore filter processing and Papanicolaou staining technique. Cytological findings comprised of macrophages (melanophages, siderophages) and inflammatory cells, mainly lymphocytes. In a few cases, pigmented an nonpigmented epithelial cells of the ciliary body were encountered, retinal sensory cells only in one case. Fibroblasts and fragments of granulation tissue occurred in four of the 14 diabetic cases, in four of the 21 posttraumatic cases, in one case of chronic uveitis as well as in one case of retrolental fibroplasia. Fragments of ciliary body were in three specimens from injured eyes. In one case of chronic uveitis slight suspicion of ciliary body melanoma was aroused on the basis of distinct cellular atypia. There was agreement between clinical and cytological diagnosis in most cases, but particularly in posttraumatic and inflammatory diseases cytologic examination offered new diagnostic data. This is a new method of microscopical verification of the condition in the vitreous body in various diseases. Our experiences are preliminary but we feel that this method has proven its availability.
Similar content being viewed by others
References
Green, W.R. Diagnostic cytopathology of ocular fluid specimens. Ophthalmology (Rochester) 91: 726 (1984).
Constable, I.J. The pathology of vitreous membranes and the effect of haemorrhage on new vessels of the vitreous. Trans. Ophthalmol. Soc. U.K. 95: 382 (1975).
Forrester, J.V. & W.R. Lee. Cellular composition of posthaemorrhagic opacities in the human vitreous. Graefes Arch. Klin. Exp. Ophthalmol. 215: 279 (1981).
Forrester, J.V., W.R. Lee & J. Williamson. The pathology of vitreous haemorrhage. Arch. Ophthalmol. 96: 703 (1978).
Cleary, P.E. & S.J. Ryan. Histology of wound, vitreous and retina in experimental posterior penetrating eye injury in the rhesus monkey. Am. J. Ophthalmol. 88: 221 (1979).
The Retina Society Terminology Committee. The classification of retinal detachment with proliferative vitreoretinopathy. Ophthalmology (Rochester) 90: 121 (1983).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Laatikainen, L., Tarkkanen, A. & Koivuniemi, A. Vitrectomy. Int Ophthalmol 7, 215–222 (1985). https://doi.org/10.1007/BF00128368
Issue Date:
DOI: https://doi.org/10.1007/BF00128368