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A complicated case of ciliary body melanoma and glaucoma

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Abstract

This clinicopathological case report describes the bilateral ocular pathology in an eldery man suffering from primary open angle glaucoma, aphakia and a ciliary body melanoma which was treated by cryotherapy to preserve vision in the better eye. Liver metastases were detected 18 months after the tumour was recognised. At autopsy, melanoma metastases were found within a renal cell carcinoma which had also metastasised to the lungs. Other abnormalities included aphakic maculopathy, senile macular degeneration, asteroid hyalosis and patchy hyalinisation of the retinal vasculature, which in one eye was the source of preretinal neovascularisation derived from intramural neovascularisation.

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References

  1. Alvarado, J., C. Murphy & R. Juster. Trabecular meshwork cellularity in primary open angle glaucoma and nonglaucomatous normals. Ophthalmology 91: 564–579 (1984).

    Google Scholar 

  2. Barr, C.C., L.E. Zimmerman, V.T. Curtin & R.L. Font. Simultaneous bilateral diffuse melanocytic tumours of the uvea associated with systemic malignancy. Arch. Ophthalmol. 100: 249–254 (1981).

    Google Scholar 

  3. Ballantyne, A.J. New formed vessels in the fundus oculi. Ophthalmologica 118: 611–631 (1949).

    Google Scholar 

  4. Gamel, J.W. & I.W. McLean. Modern developments in histopathologic assessment of uveal melanomas. Ophthalmology 91: 679–684 (1984).

    Google Scholar 

  5. Grierson, I., Q. Wang, P.G. McMenamin & W.R. Lee. The effects of age and antiglaucoma drugs on the meshwork cell population Res. Clin. For. 4: 69–92 (1982).

    Google Scholar 

  6. Kerston, R.C. Management of choroidal malignant melanoma at Iowa. Ophthalmologica 189: 24–35 (1984).

    Google Scholar 

  7. Lee, W.R. & I. Grierson. Ch. 17. Anterior segment changes in glaucoma. In: Pathobiology of Ocular Disease, pp. 525–551. Eds. Garner A. & G.K. Klintworth. Dekker, N.Y. (1982).

    Google Scholar 

  8. Lommatzsch, P.K. & F.C. Blodi. Eds. Intraocular Tumours. Springer-Verlag, Berlin (1983).

    Google Scholar 

  9. Lowenstein, A. Intramural vessels and endothelial cells in the walls of sclerosed retinal arteries. Br. J. Ophthalmol. 34: 594–600 (1950).

    Google Scholar 

  10. Manschot, W.A. & H.A. van Peperzeel. Choroidal melanoma. Enucleation or observation? A new approach. Arch. Ophthalmol. 98: 71–77 (1980).

    Google Scholar 

  11. Manschot, W.A. & W.R. Lee. Retinal neovascularisation arising from hyalinised blood vessels. Graefes Arch. Clin. Exp. Ophthalmol. 222: 63–70 (1984).

    Google Scholar 

  12. Schepens, C.L., M.P. Avila, A.E. Jalkh & C.L. Trempe. Role of the vitreous in cystoid macular oedema. Surv. Ophthalmol. 28: 499–504 (1984).

    Google Scholar 

  13. Tso, M.O.M. Animal modeling of cystoid macular oedema. Surv. Ophthalmol. 28: 512–519 (1984).

    Google Scholar 

  14. Yanoff, M., B.S. Fine, A.J. Brucker & R.C. Eagle. Pathology of human cystoid macular oedema. Surv. Ophthalmol. 28: 505–511 (1984).

    Google Scholar 

  15. Zimmerman, L.E., I.W. McLean & W.D. Foster. Does enucleation of the eye containing a melanoma prevent or accelerate the dissemination of tumour cells? Br. J. Ophthalmol. 62: 420–425 (1978).

    Google Scholar 

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Lee, W.R., Jay, J.L. A complicated case of ciliary body melanoma and glaucoma. Int Ophthalmol 7, 175–181 (1985). https://doi.org/10.1007/BF00128364

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