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Regulation of lysine excretion in the lysine producer strain Corynebacterium glutamicum MH 20-22B

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Summary

Lysine excretion by the producer strain Corynebacterium glutamicum MH 20-22B was analyzed in relation to the internal lysine concentration. In contrast to the wild-type, lysine excretion in the producer strain was allosterically regulated by internal lysine. The apparent Hill coefficient of 1.3 – 2.2 indicates the presence of at least two cooperatively interacting lysine binding sites.

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Authors and Affiliations

  1. Institut für Biotechnologie I, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany

    Andreas Erdmann, Brita Weil & Reinhard Krämer

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  1. Andreas Erdmann
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  2. Brita Weil
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  3. Reinhard Krämer
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Erdmann, A., Weil, B. & Krämer, R. Regulation of lysine excretion in the lysine producer strain Corynebacterium glutamicum MH 20-22B. Biotechnol Lett 17, 927–932 (1995). https://doi.org/10.1007/BF00127428

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  • DOI: https://doi.org/10.1007/BF00127428

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