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A study of the inhibition of an amidase with a wide substrate spectrum and its consequences for the bioconversion of nitriles

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Summary

TheBrevibacterium sp. R 312 strain possesses a nitrile-hydratase and an amidase, both with a wide substrate spectrum. These two enzymes can be used for the bioconversion of nitriles into the corresponding organic acids: the actions of three types of compounds (nitriles, amides and acids) on the activity of the amidase are reported in the present work.

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Maestracci, M., Bui, K., Thiéry, A. et al. A study of the inhibition of an amidase with a wide substrate spectrum and its consequences for the bioconversion of nitriles. Biotechnol Lett 6, 149–154 (1984). https://doi.org/10.1007/BF00127030

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