On the genetics of an esterase polymorphism of Saccharomyces cerevisiae. The inheritance of unspecific esterases of Saccharomyces cerevisae was investigated by tetrad analysis. It was shown that the four bands, found in the strains investibated, and distinguished by their electrophoretic mobility, are controlled by two loci with two alleles each. The loci E1 and E2 segregate independently whereas E2 is closely linked to the ad2 locus. The E1 locus could not be mapped; however, there was evidence for free recombination with the contromere.
Similar content being viewed by others
Literatur
Berking, S. & P. Hauschild-Rogat (1970). Series Dise Electrophoresis. Its application to enzyme research. Analyt. Biochem. 36: 227–233.
Brown, A. H. D. & R. W. Allard (1969). The inheritance of isozyme differences among the inbred parents of a reciprocal recurrent selection population of corn. Crop. Sci. 9: 72–75.
Desborough, S. & G. Lindegren (1959). Chromosome mapping of linkage data from Saccharomyces by tetrad analysis. Genetica, 30: 346–383.
Gutz, H. & C. C. Emeis (1959). Saccharomyces als Objelct für populationsgene-tische Versuche. Z. Naturf. 14b: 457–460.
Haefner, K. (1967). A simple apparatus for producing agar layers of uniform thickness for microbiological micromanipulator work. Z. ailg. Mikrobiol. 3: 229–231.
Hubby, J. L. & R. C. Lewontin (1966). A molecular approach to the study of genetic heterozygosity in natural populations. I. The number of alleles at different loci in Drosophila pseudoobscura. Genetics 54: 577–594.
Hwang, Y. L., G. Lindegren & C. C. Lindegren (1964). The twelfth chromosome of Saccharomyces. Canad. J. Genet. Cytol. 6: 373–380.
Johnston, J. R. & R. K. Mortimer (1959). Use of snail digestive juice in isolation of yeast spore tetrads. J. Bacteriol., 78: 292.
Kojima, K. & K. M. Yarbrough (1967). Frequency dependent selection at the 0 Esterase 6 locus in Drosophila melanogaster. Proc. natn. Acad. Sci. U.S.A. 57: 645–649.
Kojima, K. & Y. N. Tobari (1969). The pattern of viability changes associated with genotypic frequency at the alcohol dehydrogenase locus in a population of Drosophila melanogaster. Genetics 61: 201–209.
Kojima, K., J. Gillespie & Y. N. Tobari (1970). A profile of Drosophila species enzymes assayed by electrophoresis. 1. Number of alleles, heterozygosities and linkage disequilibiium in glucose-metabolising systems and some other enzymes. Biochem. Genet. 4: 627–637.
Lewontin, B. C. & J. L. Hurey (1966). A molecular approach to the study of genetic heterozygesity in natural populations. II. Amount of variation and degree of heterozygosity in natural populations of Drosophila pseudoobscura. Genetics 54: 596–609.
Lingens, F. & O. Oltmanns (1964). Erzeugung und Untersuchung biochemischer Mangelmutanten von Saccharemyces cerevisiae. Z. Naturf. 19b: 1058–1065.
Marshall, D. R. & R. W. Allard (1970). Maintenance of isozyme polymorphisms in natural populations of Avena barbata. Genetics 66: 393–399.
Marshall, D. R. & R. W. Allard (1970). Isozyme polymorphisms in natural populations of Avena fatua and Avena barbata. Heredity 25: 373–382.
Mortimer, R. K. & D. C. Hawthorne (1966). Genetic mapping in Saccharomyces. Genetics 53: 165–173.
Perkins, D. D. (1949). Biochemical mutants in the smut fungus Ustilago maydis. Genetics 34: 607–626.
Prakash, S. & R. C. Lewontin (1968). A molecular approach to the study of genetic heterozygosity in natural populations. III. Direct evidence of coadaptation in gene arrangoments of Drosophila. Proc. natn. Acad. Sci. U.S.A. 50: 398–405.
Prakash, S., R. C. Lewontin & J. L. Hubby (1969). A molecular approach to the study of genetic heterozygosity in natural populations. IV. Patterns of genetic variation in central, marginal and isolated populations of Drosophila pseudoobscura. Genetics 61: 841–858.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Strorel, R., Wöhrmann, K. Untersuchungen zur Genetik eines Esterasepolymorphismus bei Saccharomyces cerevisiae . Genetica 43, 274–281 (1972). https://doi.org/10.1007/BF00123634
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00123634