Abstract
The basitarsal bristle pattern of the mutants sx (sexcombless), tra (transformer), and dsx (doublesex), and of the combinations sx-dsx and tra-dsx is described. Epistasis of dsx over both sx and tra for many of the chaetotaxal characteristics was found. The various effects of interaction observed, in individuals of male as well as female chromosomal constitution, are discussed in the light of the levels of action of the mutant genes in modifying the development of sex. It is suggested that intersexes induced by dsx are a class by itself, and that the action of dsx might be at a primary level of sex determination.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Anders G. (1955). Untersuchungen über das pleiotrope Manifestationsmuster der Mutante lozenge-clawless (lz et) von Drosophila melanogaster. Z. indukt. Abstamm.- u. Vererb.lehre 87: 113–186.
Bridges, C. B. & K. B. Brehme (1944). The mutants of Drosophila melanogaster. Carnegie Inst. Wash. Publ. 552.
Brown E. H. & R. C. King (1961). Studies on the expression of the transformer gene of Drosophila melanogaster. Genetics 46: 143–156.
Datta, R. K. (1969). Developmental genetics of sexcomb and bristle pattern mutants and genetic control of differentiation in Drosophila, D. Phil. Thesis, Univ. of Calcutta, Calcutta (Unpublished).
Dobzhansky Th. (1930). Studies on the intersexes and supersexes in Drosophila melanogaster. Izv. Byuro Genet. Eugen. 8: 91–158 (In Russian).
Dobzhansky Th. & J. Schultz (1934). The distribution of sex-factors in the X-chromosome of Drosophila melanogaster. J. Genet. 28: 349–386.
Hadorn, E. (1965). Problems of determination and transdetermination. In: Genetic control of differentiation. Brookhaven Symp. Biol. 18: 148–161.
Hildreth P. E. (1965). Doublesex, a recessive gene that transforms both males and females of Drosophila into intersexes. Genetics 51: 659–678.
Hollingsworth M. J. (1964). Sexcomb of intersexes and the arrangement of the chaetae on the legs of Drosophila. J. Morph. 115: 35–52.
Lakhotia S. C. & A. S. Mukherjee (1969). Chromosomal basis of dosage compensation in Drosophila. I. Cellular autonomy of hyperactivity of the male X-chromosome in salivary glands and sex differentiation. Genet. Res. 14: 137–150.
Mukherjee A. S. (1965). The effects of sexcombless on the forelegs of Drosophila melanogaster. Genetics 51: 285–304.
Mukherjee A. S. & N. Mitra (1967). Effect of the mutant sexcombless on the posterior legs of Drosophila melanogaster. J. Cytol. Genet. 2: 103–113.
Novitski E. (1951). Autonomy of the sterility of transformed females. Drosophila Information Service 25: 121.
Pipkin S. B. (1940). Multiple sex genes in the X-chromosome of Drosophila melanogaster. Univ. Texas Publ. 4032: 126–156.
Pipkin S. B. (1947). A search for sex genes in the second chromosome of Drosophila melanogaster, using the triploid method. Geneties 32: 592–607.
Pipkin S. B. (1959). Sex balance in Drosophila melanogaster: aneuploidy of short regions of chromosome 3, using the triploid method. Univ. Texas Publ. 5014: 69–88.
Pipkin S. B. (1960). Sex balance in Drosophila melanogaster: aneuploidy of long regions of chromosome 3, using the triploid method. Geneties 45: 1205–1216.
Seidel S. (1963). Untersuchungen über die Grundlagen der Sterllität von transformer (tra) Männchen bei Drosophila melanogaster. Z. Vererbungsl, 94: 215–241.
Stern C. (1965). Section 6: Developmental genetics. Synthesis by the chairman. Proc. XIth Int. Cong. Genet. 2: 221–226.
Sturtevant A. H. (1945). A gene in Drosophila melanogaster that transforms females into males. Genetics 30: 297–299.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mukherjee, A.S., Hildreth, P.E. Interaction of the mutants sx, tra and dsx in Drosophila melanogaster. Chaetotaxy of the basitarsus of the forelegs in males and females. Genetica 42, 338–352 (1971). https://doi.org/10.1007/BF00123328
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00123328