An experimental animal model was used to evaluate the value of resorbable, non-permeable polyglycolic acid (PGA) membranes in relation to fixtures implanted into simulated extraction sockets. Brånemark fixtures (length 7.0 mm, diameter 3.75 mm) were implanted into edentulous areas of maxillary bone in six sheep. Five fixtures were covered with 0.15-mm-thick PGA membrane (Biofix®) held in place with a cover screw (PGA group) and five were implanted without membrane (control group). The animals were killed after 4 months and undecalcified mesiodistal sections were prepared from resected jaw specimens. Histomorphometry was used to measure the distance from the shoulder of the fixture to the level of intimate bone contact (SB distance). SB distance was found to be greater in the PGA than in the control group in relation both to the mesial (1.44 ± 0.88 mm versus 0.96 ± 0.47 mm) and distal (1.13 ± 0.80 mm versus 0.77 ± 0.63 mm) aspects of implants. This statistically not significant difference in bone regeneration between the two groups is related to the physical properties of the PGA membrane used.
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Muhonen, J., Suuronen, R., Oikarinen, V.J. et al. Effect of polyglycolic acid membrane on bone regeneration around titanium implants inserted in bone sockets. J Mater Sci: Mater Med 5, 40–42 (1994). https://doi.org/10.1007/BF00121152
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DOI: https://doi.org/10.1007/BF00121152