A population-based case-control study of bladder cancer (2,982 cases and 5,782 controls) conducted in 10 areas of the United States examined the effect of smoking as a risk factor among Blacks and Whites, after adjustment for occupation and other potential confounders. Although the overall risk for smoking was slightly higher in Blacks than Whites (relative risk = 2.7 and 2.2, respectively), this difference was not statistically significant. Estimation of risk by dose and currency of exposure revealed no consistent racial disparities in smoking-related risks. Race-specific, attributable risk estimates indicated that nearly half of bladder cancers among both Blacks and Whites could have been prevented by elimination of smoking.
References
Ries LAG, Hankey BF, Miller BA, Hartman AM, Edwards BK. Cancer Statistics Review 1973–88. Bethesda MD: National Cancer Institute, 1991; NIH Pub. No. 91–2789.
Hartge P, Cahill JI, West D, et al. Design and methods in a multi-center case-control interview study. Am J Public Health 1984; 74: 52–6.
Schairer C, Hartge P, Hoover RN, Silverman DT. Racial differences in bladder cancer risk: a case-control study. Am J Epidemiol 1988; 128: 1027–37.
Burns PB, Swanson GM. Risk of urinary bladder cancer among Backs and Whites: the role of cigarette use and occupation. Cancer Causes Control 1991; 2: 371–9.
Harris RE, Chen-Backlund J, Wynder EL. Cancer of the urinary bladder in blacks and whites. Cancer 1990; 66: 2573–680.
Hartge P, Silverman DT, Hoover R, et al. Changing cigarette habits and bladder cancer risk: a case-control study. JNCI 1987; 78: 1119–25.
Silverman DT, Levin LI, Hoover RN. Occupational risks of bladder cancer in the United States: II. Non-white men. JNCI 1989; 81: 1480–3.
Silverman DT, Levin LI, Hoover RN. Occupational risks of bladder cancer among white women in the United States. Am J Epidemiol 1990; 132: 453–61.
Silverman DT, Levin LI, Hoover RN, Hartge P. Occupational risks of bladder cancer in the Untied States: I. White men. JNCI 1989; 81: 1472–80.
Rothman KJ. Modern Epidemiology. Boston: Little, Brown, and Co, 1986: 289–95.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hartge, P., Silverman, D.T., Schairer, C. et al. Smoking and bladder cancer risk in Blacks and Whites in the United States. Cancer Causes Control 4, 391–394 (1993). https://doi.org/10.1007/BF00051343
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00051343