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Calcium channel blocker debate: True lies?

  • Editorial: Focus on Calcium Antagonists
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References

  1. Furberg CD, Psaty BM, Meyer JV. Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. Circulation 1995;92:1326–1331.

    Google Scholar 

  2. Psaty BM, Heckbert SR, Koepsell TD, Siscovick DS, Raghunathan TE, Weiss NS. The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA 1995;274:620–625.

    Google Scholar 

  3. Buring JE, Glynn RJ, Hennekens CH. Calcium channel blockers and myocardial infarction. A hypothesis formulated but not yet tested. The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA 1995;274:654–655.

    Google Scholar 

  4. Habib GB. Are calcium antagonists harmful in hypertensive patients? Distinguishing hype from reality. Chest 1955;108:3–5.

    Google Scholar 

  5. Kloner RA. Nifedipine in ischemic heart disease. Circulation 1995;92:1074–1078.

    Google Scholar 

  6. Opie LH, Messerli FH. Nifedipine and mortality. Grave defects in the dossier. Circulation 1995;92:1068–1073.

    Google Scholar 

  7. Epstein M. Calcium antagonists should continue to be used for first-line treatment of hypertension. Arch Intern Med 1995;155:2150–2156.

    Google Scholar 

  8. HINT Research Group (Holland Interuniversity Nifedipine/Metoprolol Trial). Early treatment of unstable angina in the coronary care unit: A randomized double-blind placebo-controlled comparison of recurrent ischemia in patients treated with nifedipine or metoprolol or both. Br Heart J 1986;56:400–413.

    Google Scholar 

  9. Kloner RA, Vetroyce G. Long acting calcium channel blockers nifedipine GITS and amlodipine in hypertension-rate of myocardial infarction (abstr). J Am Coll Cardiol 1996;27 Suppl A:177A-178A.

    Google Scholar 

  10. Messerli FH, Boden WE, Hansen JF, Schechtma KB. Heart rate lowering calcium antagonists (HRL-CA) in hypertensive post MI patients (abstr). J Am Coll Cardiol 1996;27 Suppl A:178A.

  11. Boden WE, Messerli FH, Hansen JF, Schechtma KB. Heart rate lowering calcium channel blockers (diltiazem, verapamil) do not adversely affect long-term cardiac death or non-fatal infarction in post-infarction patients: Data pooled from 3 randomized, placebo-controlled clinical trials (abstr). J Am Coll Cardiol 1996;27 Suppl A:319A.

  12. Braun S, Boyko V, Behar S, et al. Calcium antagonists and mortality in patients with coronary artery disease: A cohort study of 11,575 patients. J Am Coll Cardiol 1996;28:7–11.

    Google Scholar 

  13. Held PH, Yusuf S. Calcium antagonists in the treatment of ischemic heart disease: Myocardial infarction. Cor Art Dis 1994;5:21–26.

    Google Scholar 

  14. Pilote L, Califf RM, Sapp S, et al. and GUSTO-1 Investigators. Regional variation across the United States in the management of acute myocardial infarction. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. N Engl J Med 1995;333:565–572.

    Google Scholar 

  15. Mahaffey KW, GUSTO Investigators. Underuse of ACE inhibitors and overuse of calcium channel blockers in acute myocardial infarction patients: Results from two randomized international trials (abstr). Circulation 1995;92(Suppl):I206.

  16. Mahaffey KW. Underuse of ACE inhibitors and overuse of calcium channel blockers in acute myocardial infarction patients: Results from two randomized international trials. ACCEL 1995:December: 27.

  17. Braunwald E, Jones RH, Mark DB, et al. Diagnosing and managing unstable angina. Agency for Health Care Policy and Research. Circulation 1994;90:613–622.

    Google Scholar 

  18. Schreiber TL, Elkhatib A, Grines CL, O'Neill WW. Cardiologist versus internist management of patients with unstable angina: Treatment patterns and outcomes. J Am Coll Cardiol 1995;26:577–582.

    Google Scholar 

  19. Woods KL. Mega-trials and management of acute myocardial infarction. Lancet 1995;346:611–614.

    Google Scholar 

  20. Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure. The fifth report of the Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure (JNC V). Arch Intern Med 1993;153:154–183.

    Google Scholar 

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Leor, J., Battler, A. Calcium channel blocker debate: True lies?. Cardiovasc Drug Ther 10, 413–415 (1996). https://doi.org/10.1007/BF00051105

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  • DOI: https://doi.org/10.1007/BF00051105

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