Skip to main content
SpringerLink
Log in

Biological activity in Macrocystis pyrifera from Argentina: sodium alginate, fucoidan and laminaran. II. Genotoxicity

  • Chemical composition and properties
  • Published:
Hydrobiologia Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Babich, H., M. A. Devanas & G. Stotzky, 1985. The mediation of mutagenicity and clastogenicity of heavy metals by physicochemical factors. Envir. Res. 37: 253–286.

    Google Scholar 

  • Bliss, C. I., 1967. Statistics in Biology. Vol. 1. McGraw-Hill, New York.

    Google Scholar 

  • Kashiwagi, J., J. S. Mynderse, R. E. Moore & T. R. Norton, 1980. Antineoplastic evaluation of Pacific marine algae. J. Pharm. Sci. 69: 735–738.

    Google Scholar 

  • Larripa, I., M. Mudry de Pargament, M. L. Labal de Vinuesa, A. Demattei & S. Brieux de Salum, 1984. In vivo and in vitro cytogenetic effects of the antitumor agent Amsacrina (AMSA). Mutat. Res. 138: 87–91.

    Google Scholar 

  • Leonard, A., G. B. Gerber, P. Jacquet & R. R. Lauwerys, 1984. Carcinogenicity, mutagenicity and teratogenicity of industrially used metals. In M. Kirsch-Volders (ed.), Mutagenicity, Carcinogenicity and Teratogenicity of Industrial Pollutants. Plenum Press, New York: 59–126.

    Google Scholar 

  • Mayer, A. M. S. & B. Panick, 1984. Antitumor evaluation of marine algae in Argentina. Proc. int. Seaweed Symp. 11: 529–533.

    Google Scholar 

  • Mayer, A. M. S., L. Krotz, R. D. Bonfil, O. D. Bustuoabad, J. F. Groisman, R. M. de Lederkremer & D. Stierle, 1987. Biological activity in Macrocystis pyrifera from Argentina, sodium alginate, fucoidan and laminaran. I. Antitumor, cytotoxicity and humoral immune response. Proc. int. seaweed Symp. 12: 483–489.

    Google Scholar 

  • Mayer, A. M.S., B. Panick, R. D. Bonfil, M. A. Espeche, E. R. Fraile, A. Diaz, A. Pesce, M. Criscuolo, J. F. Groisman & R. M. de Lederkremer, 1986. Screening of antitumor, cytotoxic, immunologic, antimicrobial and antiviral activity in Macrocystis pyrifera, a Patagonian marine alga of economic importance. Actas II Congr. Algas Mar. Chilenas (in press). 177–183.

  • Nichols, W. W., 1972. Chromosome methodologies in mutation testing. Toxicol. appl. Pharm. 22: 269–275.

    Google Scholar 

  • Paskins-Hulburt, A. J., S. C. Skoryna, Y. Tanaka, W. Moore jr. & J. F. Stara, 1978. Fucoidan: its binding of lead and other metals. Bot. mar. 21: 13–22.

    Google Scholar 

  • Schmid, W., 1975. The micronucleus test. Mutat. Res. 31: 9–15.

    Google Scholar 

  • Stein, J. R. & C. A. Borden, 1984. Causative and beneficial algae in human disease conditions: a review. Phycologia 23: 485–501.

    Google Scholar 

  • Suffness, M., 1985. The discovery and development of antitumor drugs from natural products. In A. J. Vlietinck & R. A. Dommisse (eds), Advances in Medicinal Plant Research. Wissenschaftliche Verlagsgesellschaft GmbH, Stuttgart: 101–133.

    Google Scholar 

  • Usui, T., K. Asari & T. Mizuno, 1980. Isolation of a highly purified “fucoidan” from Eisenia bicyclis and its anticoagulant and antitumor activities. Agr. Biol. Chem. 44: 1965–1966.

    Google Scholar 

  • Yamamoto, I., M. Takahashi, T. Suzuki, H. Seino & H. Mori, 1984. Antitumor effect of seaweeds. IV. Enhancement of antitumor activity by sulfation of a crude fucoidan fraction from Sargassum kjellmanianum. Japn. J. exp. Med. 54: 143–151.

    Google Scholar 

  • Yamamoto, I. & H. Maruyama, 1985. Effect of dietary seaweed preparations on 1,2-dimethylhydrazine-induced intestinal carcinogenesis in rats. Cancer Lett. 26: 241–251.

    Google Scholar 

Download references

Author information

Author notes

  1. Alejandro M. S. Mayer

    Present address: Department of Biological Sciences, University of California at Santa Barbara, 93106, Santa Barbara, California, USA

Authors and Affiliations

  1. Seccion Citogenetica, Instituto de Investigaciones Hematologicas, Academia Nacional de Medicina, Las Heras 3092, 1425, Buenos Aires, Argentina

    Marta Mudry de Pargament

  2. Centro Austral de Investigaciones Cientificas-CONICET, Ushuaia, Tierra del Fuego, Argentina

    Mabel Labal de Vinuesa

  3. PLEX-CONICET, Instituto de Investigaciones Hematologicas, Academia Nacional de Medicina, Las Heras 3092, 1425, Buenos Aires, Argentina

    Alejandro M. S. Mayer

Authors
  1. Irene B. Larripa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Marta Mudry de Pargament
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mabel Labal de Vinuesa
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Alejandro M. S. Mayer
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Larripa, I.B., de Pargament, M.M., de Vinuesa, M.L. et al. Biological activity in Macrocystis pyrifera from Argentina: sodium alginate, fucoidan and laminaran. II. Genotoxicity. Hydrobiologia 151, 491–496 (1987). https://doi.org/10.1007/BF00046172

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00046172

Key words

Search

Navigation