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Peptides in the Hydrozoa: are they transmitters?

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  • XII. Physiology and behaviour Transmitters
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Abstract

A family of peptides with the carboxy-terminus Arg-Phe-amide has been localized to specific subpopulations of neurons in every cnidarian species examined. These neurons are typically sensory in character or are associated with smooth muscle. Although a transmitter role for these peptides has been suggested for anthozoans at neuromuscular synapses, no such evidence is available for hydrozoans. Instead there is evidence that RF-amides can be modulators of neuronal activity which takes the form of a biphasic (inhibitory then excitatory) response in vivo, while in vitro only the inhibitory response is seen. Voltage clamp studies of identified motor neurons showed large, transitory outward currents when Pol-RF-amide peptide was applied.

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  1. Department of Zoology, University of Alberta, T6G 2E9, Edmonton, Alberta, Canada

    A. N. Spencer

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Spencer, A.N. Peptides in the Hydrozoa: are they transmitters?. Hydrobiologia 216, 565–571 (1991). https://doi.org/10.1007/BF00026514

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