Abstract
Callus growth, in tobacco pith tissue culture, is activated by p-dimethylaminoazobenzene (p-DAAB), whose carcinogenic properties are well known. Ultrastructural changes, appearing in a period prior to initiation of cell proliferation, occur earlier and more intensely in the presence of the carcinogen. This also influences changes in non-histone chromatin proteins (NHCP). Doxorubicin (DR), an anti-tumor drug, inhibits callus growth and modifies the pattern of NHCP.
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Culiáñez-macià, F.A., Primo-Millo, E., Hernández-Yago, J. et al. Influence of p-dimethylaminoazobenzene and doxorubicin on tobacco cell growth (Nicotiana tabacum L.). Plant Growth Regul 5, 155–164 (1987). https://doi.org/10.1007/BF00024742
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DOI: https://doi.org/10.1007/BF00024742