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Unusual presentation of recurrent papillary thyroid microcarcinoma with neck muscle and skin metastasis

  • Alessandro Sindoni
  • Carlo Gobitti
  • Sandro Sulfaro
  • Vittorio Giacomarra
  • Eugenio Borsatti
Letter to the Editor
  • 2 Downloads

Dear Sir,

Papillary thyroid microcarcinoma is commonly considered to have a good prognosis. We report the case of a 47-year-old male patient, who was referred to our Institution for a papillary thyroid microcarcinoma infiltrating perithyroidal fibroadipose tissue, treated in 2006 with surgery and in 2007 with 131I-therapy (3700 MBq). He was followed up between 2007 and 2017 and was free of disease based on serum Tg and ultrasonography; then, suddenly, some pimple-like neck skin lesions appeared that were not responsive to topical therapy.

The patient underwent excision of these skin lesions, which at histopathology were found to originate from papillary thyroid carcinoma. A subsequent neck ultrasonography revealed a 9 × 4-mm nodule in the sternothyroid muscle and a 4-mm nodule in the sternocleidomastoid muscle (Fig.  1). Diagnostic 131I whole-body scan performed after recombinant human TSH (rhTSH) stimulation was negative (Fig.  2a, b), but serum Tg was detectable (16/02/2018:TSH...

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All diagnostic and therapeutic procedures performed in this study were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Declaration of Helsinki and its later amendments, or comparable ethical standards.

Informed consent

Informed consent was obtained from the individual participants included in the study.

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Copyright information

© Hellenic Endocrine Society 2018

Authors and Affiliations

  • Alessandro Sindoni
    • 1
  • Carlo Gobitti
    • 2
  • Sandro Sulfaro
    • 3
  • Vittorio Giacomarra
    • 4
  • Eugenio Borsatti
    • 1
  1. 1.Nuclear Medicine UnitCRO Aviano National Cancer InstituteAvianoItaly
  2. 2.Radiotherapy UnitCRO Aviano National Cancer InstituteAvianoItaly
  3. 3.Pathology Unit“Santa Maria Degli Angeli” HospitalPordenoneItaly
  4. 4.Otorhinolaryngology Unit“Santa Maria Degli Angeli” HospitalPordenoneItaly

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