Journal of the Australian Ceramic Society

, Volume 55, Issue 1, pp 229–234 | Cite as

Effect of Joncryl61 and gelatin in the formation of hydroxyapatite nanocomposite

  • B. Shalini
  • A. Ruban KumarEmail author


Hydroxyapatite (HAp) is a bioceramic known for bone applications due to its physical and chemical properties similar to the human bone. In this present study, HAp nanopowder was synthesised using chemical precipitation method in the presence of polymers Joncryl61 (acrylic resin) and gelatin (biopolymer). The crystalline nature of synthesised pure and polymer-added hydroxyapatite was confirmed by powder X-ray diffraction pattern and the FTIR pattern peaks present at 604–624 cm−1 revealing the presence of phosphate phase. Morphological studies using SEM revealed the presence of rod-shaped, agglomerated rod-shaped and rod shape with small sphere dumbbell structure in pure HAp, HAp with Joncryl61 and HAp with gelatin respectively. The dielectric properties of pure and polymer-doped HAp were also examined at room temperature with frequency from 50 to 5,000,000 Hz. The dielectric constant and loss were found to be maximum when the frequency was low.


Hydroxyapatite Joncryl61 Structural FTIR Morphology 



The authors excitedly recognised VIT University for providing support and excellent research facilities.


  1. 1.
    Zhou, H., Lee, J.: Nanoscale hydroxyapatite particles for bone tissue engineering. Acta Biomater. 7(7), 2769–2781 (2011)CrossRefGoogle Scholar
  2. 2.
    Jiao, Y., Lu, Y.P., Xiao, G.Y., Xu, W.H., Zhu, R.F.: Preparation and characterization of hollow hydroxyapatite microspheres by the centrifugal spray drying method. Powder Technol. 217, 581–584 (2012)CrossRefGoogle Scholar
  3. 3.
    Del Real, R.P., Wolke, J.G.C., Vallet-Regı, M., Jansen, J.A.: A new method to produce macropores in calcium phosphate cement. Biomaterials. 23(17), 3673–3680 (2002)CrossRefGoogle Scholar
  4. 4.
    Tahriri, M., Solati-Hashjin, M., Eslami, H.: Synthesis and characterisation of hydroxyapatite nanocrystals via chemical precipitation technique. Iran. J. Pharm. Res. 4(2), 127–134 (2008)Google Scholar
  5. 5.
    Ramli, R.A., Adnan, R., Bakar, M.A., Masudi, S.A.M.: Synthesis and characterisation of pure nanoporous hydroxyapatite. J. Phys. Sci. 22(1), 20–37 (2011)Google Scholar
  6. 6.
    Agrawal, K., Singh, G., Puri, D., Prakash, S.: Synthesis and characterisation of hydroxyapatite powder by a sol-gel method for biomedical application. J. Miner. Mater. Charact. Eng. 10(08), 727 (2011)Google Scholar
  7. 7.
    Eslami, H., Tahriri, M., Bakhshi, F.: Synthesis and characterization of nanocrystalline hydroxyapatite obtained by the wet chemical technique. Mater. Sci. Pol. 28(1), 5–13 (2010)Google Scholar
  8. 8.
    Selestina, G., Vanja, K.: Collagen- vs gelatine-based biomaterials and their biocompatibility: review and perspectives. In: Pignatello, R. (ed.) Biomaterials applications for nanomedicine, pp. 17–53. INTECH Open Access Publisher (2011).
  9. 9.
    Fathi, M.H., Hanifi, A.: Evaluation and characterization of nanostructure hydroxyapatite powder prepared by the simple sol-gel method. Mater. Lett. 61(18), 3978–3983 (2007)CrossRefGoogle Scholar
  10. 10.
    Kim, I.S., Kumta, P.N.: Sol-gel synthesis and characterization of nanostructured hydroxyapatite powder. Mater. Sci. Eng. B. 111(2), 232–236 (2004)CrossRefGoogle Scholar
  11. 11.
    Mobasherpour, I., Heshajin, M.S., Kazemzadeh, A., Zakeri, M.: Synthesis of nanocrystalline hydroxyapatite by using precipitation method. J. Alloys Compd. 430(1), 330–333 (2007)CrossRefGoogle Scholar
  12. 12.
    Chung, J. H., Kim, Y. K., Kim, K. H., Kwon, T. Y., Vaezmomeni, S. Z., Samiei, M., ... & Akbarzadeh, A. Synthesis, characterisation, biocompatibility of hydroxyapatite–natural polymers nanocomposites for dentistry applications. Artif. Cells Nanomed. Biotechnol. 44(1), 277–284 (2016)Google Scholar
  13. 13.
    Anitha, P., Pandya, H.M.: Comprehensive review of preparation methodologies of nano-hydroxyapatite. J. Environ. Nanotechnol. 3(1), 101–121 (2013)Google Scholar
  14. 14.
    Palanivelu, R., Kumar, A.R.: Synthesis, characterisation, in vitro antiproliferative and hemolytic activity of hydroxyapatite. Spectrochim. Acta A Mol. Biomol. Spectrosc. 127, 434–438 (2014)CrossRefGoogle Scholar
  15. 15.
    Chavan, P.N., Bahir, M.M., Mene, R.U., Mahabole, M.P., Khairnar, R.S.: Study of nanobiomaterial hydroxyapatite in simulated body fluid: formation and growth of apatite. Mater. Sci. Eng. B. 168(1), 224–230 (2010)CrossRefGoogle Scholar
  16. 16.
    Ragu, A., & Sakthivel, P. Synthesis and Characterization of Nano Hydroxyapatite with Polymethyl methacrylate Nanocomposites for Bone Tissue Regeneration. International Journal of Science and Research (IJSR) 3(11), 2282–2285 (2014)Google Scholar
  17. 17.
    Matković, T., Matković, P., Malina, J.: Effects of Ni and Mo on the microstructure and some other properties of Co–Cr dental alloys. J. Alloys Compd. 366(1), 293–297 (2004)CrossRefGoogle Scholar
  18. 18.
    Sivakumar, M., Rao, K.P.: Preparation, characterisation and in vitro release of gentamicin from coralline hydroxyapatite–gelatin composite microspheres. Biomaterials. 23(15), 3175–3181 (2002)CrossRefGoogle Scholar
  19. 19.
    Chang, M.C., Ko, C.C., Douglas, W.H.: Preparation of the hydroxyapatite-gelatin nanocomposite. Biomaterials. 24(17), 2853–2862 (2003)CrossRefGoogle Scholar
  20. 20.
    Lett, J.A., Sundareswari, M., Ravichandran, K.: Porous hydroxyapatite scaffolds for orthopaedic and dental applications-the role of binders. Mater. Today 3(6), 1672–1677 (2016)CrossRefGoogle Scholar
  21. 21.
    Kolanthai, E., Ganesan, K., Epple, M., Kalkura, S.N.: Synthesis of nanosized hydroxyapatite/agarose powders for bone filler and drug delivery application. Mater. Today Commun. 8, 31–40 (2016)CrossRefGoogle Scholar

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© Australian Ceramic Society 2018

Authors and Affiliations

  1. 1.Department of Physics, School of Advanced SciencesVIT UniversityVelloreIndia

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