Production of the novel fibrous structure of poly(ε-caprolactone)/tri-calcium phosphate/hexagonal boron nitride composites for bone tissue engineering
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Nanofibrous composites of the poly(ε-caprolactone) (PCL), tricalcium phosphate (TCP), and hexagonal boron nitride (h-BN) with different compositions were manufactured by using an economical and non-complicated method called electrospinning. Produced fibrous structures showed no bead formation and had a clean surface. Characterization of the composites showed that particles were successfully mixed with polymer phase. High cell activity of SaOS-2 cells on the composites was observed with SEM images. In addition, fibrous scaffolds are biocompatible with human bone tissue and are highly degradable.
KeywordsBiopolymers Biofibers Biomaterials Poly(ε-caprolactone) Composites