Microfluidic Electrochemical Devices for Biosensing

  • Noel Nesakumar
  • Srinivasan Kesavan
  • Chen-Zhong Li
  • Subbiah AlwarappanEmail author


The integration of the electrochemical detection system together with microfluidic technology is an attractive choice for the construction of miniaturized components in a single platform. Microchannel networks fabricated on conductive substrates prevent environmental contaminants and require only a tiny (µL or nL) sample for electroanalysis. Microfluidics coupled electrochemical detection system is particularly advantageous compared to traditional electrochemical sensing systems due to its flexibility, rapid analysis, low fabrication costs, ease of implementation and disposability. With these electrochemical sensing platforms, biochemical assays that require complex pre-processing of biological samples can be conducted on a chip. In this review, a comprehensive overview of the basic concepts of microfluidics and its recent applications in the design of miniaturized electrochemical sensors for biosensing applications are presented.


Microfluidics Electrochemical sensor Electrode Microchannel Fabrication 


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Copyright information

© The Nonferrous Metals Society of China 2019

Authors and Affiliations

  • Noel Nesakumar
    • 1
  • Srinivasan Kesavan
    • 1
  • Chen-Zhong Li
    • 2
  • Subbiah Alwarappan
    • 1
    Email author
  1. 1.Electrodics and Electrocatalysis DivisionCSIR-Central Electrochemical Research InstituteKaraikudiIndia
  2. 2.Nanobiosensors Laboratory, Department of Biomedical EngineeringFlorida International UniversityMiamiUSA

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