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Journal of Analysis and Testing

, Volume 2, Issue 4, pp 342–351 | Cite as

A New Concept for Regulatory Water Monitoring Via High-Performance Liquid Chromatography Coupled to High-Resolution Mass Spectrometry

  • Susanne Brüggen
  • Oliver J. SchmitzEmail author
Original Paper
  • 43 Downloads

Abstract

A combined approach of target, suspected target and non-target screening using liquid chromatography –high-resolution mass spectrometry (LC–HRMS) was used to develop a new concept for water monitoring. With the current LC–MS/MS target approach for water monitoring, all targets can be quantified, but no additional information about the sample is collected. With the new concept, it is possible to detect 97% of the target compounds with a simplified quantification method without losing accuracy. Furthermore, a suspect target screening can be performed to get broader qualitative information about the water samples. In addition, the non-target screening offers the possibility to identify unknown micropollutants. All three evaluation steps depend on the same analytical measurement so that a lot of measurement and quality assurance effort can be saved. This concept could change water monitoring and assessment, and make it much more efficiently without losing information. There is a chance to measure less but learn more about the water bodies.

Keywords

New concept for regulatory water monitoring High-resolution mass spectrometry (HRMS) Suspected target analysis Non-target analysis 

Supplementary material

41664_2018_81_MOESM1_ESM.docx (29 kb)
Supplementary material 1 (DOCX 28 kb)

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Copyright information

© The Nonferrous Metals Society of China 2018

Authors and Affiliations

  1. 1.North Rhine Westphalian State Agency for Nature, Environment and Consumer Protection, LANUVDuesseldorfGermany
  2. 2.Applied Analytical Chemistry, Faculty of ChemistryUniversity of Duisburg-EssenEssenGermany
  3. 3.Teaching and Research Center for SeparationUniversity of Duisburg-EssenEssenGermany

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