Polarization Properties of Thyroid Tissue by Polar Decomposition of Mueller Matrix

  • Rajkumar KodelaEmail author
  • Padmaja Vangala
Research Paper


Polarized light channeling through pathologically characterized and stained sections of thyroid tissue with appropriate combinations of optical elements and by using seven and four independent variable states is used to generate scattering intensities images. The recorded Mueller intensity images are processed, respectively, to acquire Mueller images and a 16-element Mueller matrix. Mueller matrix is further decomposed using polar decomposition technique and the polarization properties of thyroid tissue in terms of diattenuation, depolarization and retardance are understood. These parameters are used to classify the importance of using seven and four independent polarization variable states. This explains the expected difference that is attributed to utilization of four states of polarization when compared to seven states of polarization for thyroid tissue.


Polarimetric imaging Polar decomposition of Mueller matrix 



The authors would like to acknowledge Dr. Padma, Asst Professor in Pathology department of Gandhi Medical College, Hyderabad, India, for providing the tissue slides and for fruitful discussions.


  1. Chipman RA (1995) Polarimetry handbook of optics, Chapter 22, 2nd edn. McGraw-Hill, New YorkGoogle Scholar
  2. Collette E (1993) Polarized light fundamentals and applications, Chapter 15. Marcel Dekker, New YorkGoogle Scholar
  3. Goldstein DH (1992) Mueller matrix dual-rotating retarder polarimeter. Appl Opt 31:6676–6682CrossRefGoogle Scholar
  4. Lu SY, Chipman RA (1996) Interpretation of Mueller matrices based on polar decomposition, vol 13. Optical Society of America, Alabama, pp 1106–1113Google Scholar
  5. Luo Q, Tuchin VV, Gu M, Wang LV (2003) Photonics and imaging in biology and medicine, Proc.SPIE 5254, BellinghamGoogle Scholar
  6. Rajkumar K, Rao PK, Sunethri P Dr, Padmaja V Dr (2015) Mueller matrix imaging polarimetry—for tissue imaging presented at ICIC, ISSN-Proceedings IEEE: 978-1-4799-7165-7/15Google Scholar
  7. Shankaran V, Walsh JT Jr, Maitland DJ (2002) Comparative study of polarized light propagation in biological tissues. J Biomed Opt 7(3):300–306CrossRefGoogle Scholar
  8. Shukla P, Pradhan A (2009) Mueller decomposition images for cervical tissue: potential for discriminating normal and dysplastic states. Opt Express 17(3):1600–1609CrossRefGoogle Scholar
  9. Shurcliff WA (1992) Polarized light production and use. Oxford University Press, London (1980) Google Scholar
  10. Tuchin VV (1997) Light scattering study of tissues. Physics 40(5):495–515Google Scholar
  11. Tuchin VV, Wang LV, Zimnyakov DA (2006) Optical polarization in biomedical applications. Springer, New YorkGoogle Scholar
  12. Wang LV, Coté GL, Jacques SL (2002) Special section on tissue polarimetry. J Biomed Opt 7(3):278–397CrossRefGoogle Scholar
  13. Wright CHG, Barrett SF, Welch AJ (2002) Laser-Tissue Interaction. In: Vij DR, Mahesh K (eds) Lasers in medicine. Kluwer, BostonGoogle Scholar

Copyright information

© Shiraz University 2017

Authors and Affiliations

  1. 1.Department of Electronics and Communication Engineering, Faculty of EngineeringSR Engineering CollegeWarangalIndia
  2. 2.Department of Electronics and Communication Engineering, Faculty of EngineeringVallurupalli Nageswara Rao Vignan Jyothi Institute of Engineering and TechnologyHyderabadIndia

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