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Long-Term Survival of Advanced Breast Cancer with Letrozole and Palbociclib: Can the Intent Change from Palliation to Cure?

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We report a patient with advanced hormone-positive, HER2-negative breast cancer with contralateral supraclavicular node and subpleural lung nodules who was treated with letrozole and palbociclib with palliative intent. After 2 years of treatment, PET–CT showed disease confined only to the breast and she underwent modified radical mastectomy. Histopathology showed a 1-mm focus of invasive carcinoma. She was continued on letrozole and palbociclib and has completed 3 years since the diagnosis of metastatic disease and is in complete remission.

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Correspondence to Manikandan Dhanushkodi.

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Dhanushkodi, M., Velusamy, S. Long-Term Survival of Advanced Breast Cancer with Letrozole and Palbociclib: Can the Intent Change from Palliation to Cure?. Indian J Gynecol Oncolog 18, 28 (2020). https://doi.org/10.1007/s40944-020-0376-0

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  • Advanced breast cancer
  • Letrozole and palbociclib
  • Long-term survival