Skip to main content
Log in

Cervical Rhabdomyosarcoma with Prolapse in a Young Girl

  • Case report
  • Published:
Indian Journal of Gynecologic Oncology Aims and scope Submit manuscript

Abstract

Background

Rhabdomyosarcomas are malignant skeletal muscle tumours. They are rare in adults, but account for about 50% of soft tissue sarcomas in children. Most frequent sites include head and neck (35%), followed by the genitourinary tract (25%), extremities and trunk, and cervix is one of the least common sites in the genitourinary tract.

Case description

We report the case of a 13-year-old girl who was evaluated for excessive discharge per vaginum and was symptomatically treated and later diagnosed as a case of cervical RMS. She developed excess bleeding per vaginum associated with prolapse of the mass for which an emergency excision had to be done. Then, she completed her chemotherapy and is disease free till date.

Conclusion

We report this case due to its unusual presentation. She was initially treated as a case of vaginitis and diagnosis was missed. Once she was diagnosed as having cervical RMS and on chemotherapy, she developed prolapse of the mass with bleeding, which is also an unusual presentation. So cases of excessive discharge per vaginum not responding to treatment should have a detailed pelvic examination to rule out any mass lesions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Ognjanovic S, Linabery AM, Charbonneau B, et al. Trends in childhood rhabdomyosarcoma incidence and survival in the United States, 1975–2005. Cancer. 2009;115:4218–26.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Daya DA, Scully RE. Sarcoma botryoides of the uterine cervix in young women: a clinicopathological study of 13 cases. Gynecol Oncol. 1988;29:290–304.

    Article  CAS  PubMed  Google Scholar 

  3. Leuschner I, Harms D, Mattke A, et al. Rhabdomyosarcoma of the urinary bladder and vagina. A clinicopathologic study with emphasis on recurrent disease: a report from the Kiel Pediatric Tumor Registry and the German CWS Study. Am J Surg Pathol. 2001;25:856–64.

    Article  CAS  PubMed  Google Scholar 

  4. Walterhouse DO, Meza JL, Breneman JC, et al. Local control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children’s Oncology Group. Pediatr Blood Cancer. 2011;57:76–83.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Khosla D, Gupta R, Srinivasan R, Patel F, Rajwanshi A. Sarcomas of uterine cervix: clinicopathological features, treatment, and outcome. Int J Gynecol Cancer. 2012;22:1026–30.

    Article  PubMed  Google Scholar 

  6. Fletcher C, Bridge J, Hogendroom P, Mertrens F. WHO classification of tumours of soft tissue and bone. IARC: Lyon; 2013.

    Google Scholar 

  7. Houghton JP, McCluggage WG. Embryonal rhabdomyosarcoma of the cervix swith focal pleomorphic areas. J Clin Pathol. 2007;60:88–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Bernal KL, Fahmy L, Remmenga S, Bridge J, Baker J. Embryonal rhabdomyosarcoma (sarcoma botryoides) of the cervix presenting as a cervical polyp treated with fertility-sparing surgery and adjuvant chemotherapy. Gynecol Oncol. 2004;95:243–6.

    Article  PubMed  Google Scholar 

  9. Ghaemmaghami F, Karimi Zarchi M, Ghasemi M. Lower genital tract rhabdomyosarcoma: case series and literature review. Arch Gynecol Obstet. 2008;278:65–9.

    Article  PubMed  Google Scholar 

  10. Sanders MA, Gordinier M, Talwalkar SS, Moore GD. Embryonal rhabdomyosarcoma of the uterine cervix in a 41-year-old woman treated with radical hysterectomy and adjuvant chemotherapy. Gynecol Oncol. 2008;111:561–3.

    Article  PubMed  Google Scholar 

  11. Enzinger FM. Rhabdomyosarcoma. In: Weiss SW, editor. Soft tissue tumors. 3rd ed. CV Mosby: St Louis; 1995. p. 539–77.

    Google Scholar 

  12. Kriseman ML, Wang W-L, Sullinger J, Schmeler KM, Ramirez PT, Herzog CE, Frumovitz M. Rhabdomyosarcoma of the cervix in adult women and younger patients. Gynecol Oncol. 2012;126:351–6.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Dehner LP, Jarzembowski JA, Hill DA. Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations.

  14. Villella JA, Bogner PN, Jani-Sait SN, Block AM, Lele S. Rhabdomyosarcoma of the cervix in sisters with review of the literature. Gynecol Oncol. 2005;99:742–8.

    Article  PubMed  Google Scholar 

  15. Ferguson SE, Gerald W, Barakat RR, Chi DS, Soslow RA. Clinicopathologic features of rhabdomyosarcoma of gynecologic origin in adults. Am J Surg Pathol. 2007;31:382–9.

    Article  PubMed  Google Scholar 

  16. Zrara I, Mounzil CD, Rimani M, Bouzidi A, Labraimi A, Ben OC. Botryoide sarcoma of the uterine cervix. About one case. Gynécol Obstét Fertil. 2002;30:784–6.

    Article  CAS  PubMed  Google Scholar 

  17. Kayton ML, Wexler LH, Lewin SN, Park KJ, La Quaglia MP, Abu-rustum NR. Pediatric radical abdominal trachelectomy for anaplastic embryonal rhabdomyosarcoma of the uterine cervix: an alternative to radical hysterectomy. J Pediatr Surg. 2009;44:862–7.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Elizabeth Reshmi John.

Ethics declarations

Conflict of interest

None.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

John, E.R., Rema, P., Siva Ranjith, J. et al. Cervical Rhabdomyosarcoma with Prolapse in a Young Girl. Indian J Gynecol Oncolog 16, 65 (2018). https://doi.org/10.1007/s40944-018-0236-3

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s40944-018-0236-3

Keywords

Navigation