Mechanical and corrosion properties of partially degradable bone screws made of pure iron and stainless steel 316L by friction welding
- 78 Downloads
This paper reports a series of in vitro, ex vivo and in vivo mechanical and corrosion studies of pin and screw prototype made of friction welded pure iron and 316L type stainless steel aiming to evaluate the applicability of the partially removable bone screws. Results showed that the pin possesses bending, tensile and torsional strengths of 1706±147, 666±7 and 0.34±0.03 MPa, respectively. The pin degraded at an average weight loss rate of 17.15×10−5 g cm−2 day−1 and released Fe ions at an average concentration of 2.38 ppm. Plastic deformation induced by torsion increased the corrosion rate of the pin from 0.0014 to 0.0137 mm year−1. The maximum pull-out load of the screw prototypes was 3800 N with a calculated failure strength by shear load equal to 22.2 kN which is higher than the strength of the cortical bone. Detailed analysis of the rat’s blood cells during 60 days of the pin implantation indicated a normal response with low neutrophils/ lymphocytes ratio of 0.3‒0.5. Iron ion concentration in the rat’s blood slightly increased from 55 to 61 ppm without affecting the tissue recovering and healing phase. Histological evaluation confirmed the presence of macrophage cells as a normal response to the released iron particles around the iron section of the pin.
Keywordsbiodegradable metal bone screw friction welding iron stainless steel
This work was supported by the Malaysian Ministry of Higher Education, the Indonesian Ministry of Education and Culture and the Natural Sciences and Engineering Research Council of Canada (NSERC). The authors thank Panjaitan B, Paramitha D, Setiadi MA and Karja NWK for their help during the in vivo animal implantation and histological analysis.
- 8.Kah P, Suoranta R, Martikainen J, et al. Techniques for joining dissimilar materials: metals and polymers. Rev Adv Mater Sci, 2014, 36: 152–164Google Scholar
- 20.OrthoMed. Surgical Instruments Product Catalog. 2013Google Scholar
- 36.Ferrara LA, Ryken TC. Screw pullout testing. In An YH, Draughn RA (Eds.). Mechanical Testing of Bone and the Bone-implant Interface. Boca raton-Florida: CRC Press, 2000Google Scholar
- 41.Zdero R, Rose S, Schemitsch EH, et al. Cortical screw pullout strength and effective shear stress in synthetic third generation composite femurs. J Biomech Eng, 2007, 129: 289–293Google Scholar
- 47.Schmutz P, Quach-Vu N-C, Gerber I. Metallic medical implants: electrochemical characterization of corrosion processes. Electrochem Soc Interf, 2008, 17: 35–40Google Scholar
- 49.Paramitha D, Estuningsih S, Noviana D, et al. Distribution of Febased degradable materials in mice skeletal muscle. Eur Cell Mater, 2013, S5: 55Google Scholar