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The Ethics of Chimera Creation in Stem Cell Research

  • Insoo Hyun
Ethics in Stem/Progenitor Cell Therapeutics (S Latham, Section Editor)
  • 3 Downloads
Part of the following topical collections:
  1. Topical Collection on Ethics in Stem/Progenitor Cell Therapeutics

Abstract

Purpose of review

To summarize and clarify the main ethical issues surrounding the generation and use of human-animal chimeras in stem cell research.

Recent findings

US federal funding remains restricted for certain forms of human-animal chimera research despite the widespread promulgation and acceptance of national and international stem cell-specific research guidelines.

Summary

Stem cell-based human-animal chimera research can promote advances in basic human developmental biology, disease modeling, and new drug discoveries. National and international guidelines for this form of stem cell research have been developed over the past several years but ethical concerns persist around human dignity and the possible moral humanization of chimeric animals. These concerns can be defused and ought to be replaced with a more tractable focus on animal welfare.

Keywords

Chimeras Stem cells Ethics Research oversight Animal welfare 

Notes

Compliance with Ethical Standards

Conflict of Interest

Dr. Insoo Hyun reports no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Department of Bioethics, School of MedicineCase Western Reserve UniversityClevelandUSA

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