Sleep and Pain: the Role of Depression
Purpose of Review
Good nighttime sleep is essential for maintenance of optimal daytime functioning. When nighttime sleep is disrupted, there are countless associated daytime consequences. One of the more prominent daytime consequences of disrupted sleep is pain. While the association between sleep and pain has received great empirical attention, there is still much unknown. This paper aims to summarize and evaluate the state-of-the-science of the interrelations among sleep, pain, and mood.
Cumulative scientific evidence suggests that nighttime sleep is associated with both daytime pain and daytime mood disturbances. A growing body of research indicates that disruptions in mood may be one mechanism through which sleep disruptions are related to daytime pain. The study of common biological substrates may shed additional light on the interrelations among sleep, pain, and mood.
Mood represents an important link between sleep and pain. Future investigations would be well suited to appropriately sample a variety of indicators from the domains of sleep, pain, and mood. Studies that test triadic treatments that simultaneously address sleep, pain, and mood are needed.
KeywordsSleep Insomnia Sleep apnea Sleep problems Pain Depression Mood Affect
Joseph Dzierzewski was supported by a grant from the National Institute on Aging (K23AG049955).
Compliance with Ethical Standards
Conflict of Interest
Scott Ravyts, Sarah C Griffin, and Bruce Rybarczyk each declare no potential conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by the author.
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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