Journal of Nephrology

, Volume 30, Issue 6, pp 787–793 | Cite as

Economic burden of chronic kidney disease in Korea using national sample cohort

  • Seon-Ha Kim
  • Min-Woo JoEmail author
  • Dun-Sol Go
  • Dong-Ryeol Ryu
  • Jongha Park
Original Article



Determining the cost of a disease is one of the approaches to estimate the burden of the disease. This study was aimed to estimate the socioeconomic burden of chronic kidney disease (CKD) by CKD stages and treatment strategies in Korea.


This was a population-based study designed to estimate the cost of CKD according to CKD stages and treatment strategies from a societal perspective in Korea using multiple data sources. Costs of CKD stages III, IV, and V, hemodialysis (HD), and peritoneal dialysis (PD) were estimated with a prevalence-based method. Costs of kidney transplantation (KT) and post kidney transplantation were estimated using an incidence-based method. Costs consisted of direct medical cost, productivity loss cost due to hospitalization and outpatient visit, caregiver cost, and transportation cost.


Direct medical cost per year per patient with CKD stages III, IV, and V were 1205, 1963, and 8035 Euros, respectively. Direct medical cost per year per patient receiving HD and PD was 34,554 and 25,806 Euros, respectively. Medical cost per year per KT patient was 68,798 Euros. Direct medical cost which accounted for 70% of the total cost of CKD IV and 87% of the total cost of post KT. Cost associated with productivity loss was approximately 8–20%.


Our findings could be useful for evaluating cost-effectiveness of various CKD interventions including the screening strategy. This study also emphasizes a remarkable increase in the socioeconomic burden associated with the progression of CKD in patients.


Chronic kidney disease Cost of illness South Korea Renal replacement therapy 



This work was supported by the Research Program funded by the Korea Centers for Disease Control and Prevention (2015E3300500).

Compliance with ethical standards

Conflict of interest

The authors have no conflict of interest to declare.

Ethical approval

This study used public reports and data from statistics of Korea. Data were extracted from the administrative database of NHIC in an anonymous way. Ethical committee evaluation was not needed.

Research involving human participants and/or animals

Not applicable because this study was observational and retrospective.

Informed consent

All data of the present study regarding patients were extracted from already de-identified information from the NHIC. Therefore, informed consent was not applicable.


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Copyright information

© Italian Society of Nephrology 2017

Authors and Affiliations

  • Seon-Ha Kim
    • 1
  • Min-Woo Jo
    • 2
    Email author
  • Dun-Sol Go
    • 3
  • Dong-Ryeol Ryu
    • 4
  • Jongha Park
    • 5
  1. 1.Department of Nursing, College of NursingDankook UniversityDongnam-guSouth Korea
  2. 2.Department of Preventive Medicine, College of MedicineUniversity of UlsanSongpa-guSouth Korea
  3. 3.Department of Public Health, Graduate SchoolKorea UniversitySeongbuk-guSouth Korea
  4. 4.Department of Internal Medicine, School of MedicineEwha Womans UniversityYangcheon-guSouth Korea
  5. 5.Division of Nephrology, Department of Internal Medicine, Ulsan University HospitalUniversity of Ulsan College of MedicineUlsanSouth Korea

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