Journal of Endocrinological Investigation

, Volume 42, Issue 1, pp 105–106 | Cite as

Should the use of neck-ultrasonography be reduced during the follow-up of differentiated thyroid cancer patients with undetectable or low (i.e., < 1 µg/L) thyroglobulin levels and negative thyroglobulin antibody?

  • A. CampennìEmail author
  • M. Tulchinsky
Letter to the Editor


Differentiated thyroid cancer Thyroglobulin Thyroglobulin anti-body Neck ultrasound 


Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

A written informed consent was obtained from each patient.


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    Pacini F, Basolo F, Bellantone R et al (2018) Italian consensus on diagnosis and treatment of differentiated thyroid cancer: joint statements of six Italian societies. J Endocrinol Investig 41(7):849–876. CrossRefGoogle Scholar
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    Yang SP, Bach AM, Tuttle RM, Fish SA (2015) Serial neck ultrasound is more likely to identify false positive abnormalities than clinically significant disease in low risk papillary thyroid cancer patients. Endocr Pract 21:1372–1379CrossRefGoogle Scholar
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    Verburg FA, Mäder U, Giovanella L, Luster M, Reiners C (2018) Low or undetectable basal thyroglobulin levels obviate the need for neck ultrasound in differentiated thyroid cancer patients after total thyroidectomy and 131I ablation. Thyroid 28(6):722–728. CrossRefPubMedGoogle Scholar

Copyright information

© Italian Society of Endocrinology (SIE) 2018

Authors and Affiliations

  1. 1.Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional ImagingUniversity of MessinaMessinaItaly
  2. 2.Section of Nuclear Medicine, Department of RadiologyPennsylvania State UniversityHersheyUSA

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