Isometric handgrip training reduces blood pressure and wave reflections in East Asian, non-medicated, middle-aged and older adults: a randomized control trial

  • Takanobu OkamotoEmail author
  • Yuto Hashimoto
  • Ryota Kobayashi
Original Article



The aim of this study was to investigate the effects of isometric handgrip (IHG) training on central and peripheral blood pressure (BP) and wave reflections in East Asian non-medicated middle-aged and older adults.


Twenty-two men and women (mean age 65 ± 11 years) who were not actively involved in regular resistance or endurance training were randomly assigned to a group that did IHG and a control (CON) group. The IHG training was comprised of four unilateral 2-min isometric contractions at 30% of maximal voluntary contraction using a programmed handgrip dynamometer with 1-min rest periods for 5 days per week for 8 weeks.


Baseline central systolic BP (cSBP), brachial systolic BP (bSBP), brachial diastolic BP (bDBP), and the augmentation index (AIx) (via an automated applanation tonometric system) did not differ significantly between the groups. Compared to baseline, cSBP, bSBP, bDBP, and AIx decreased significantly after the 8-week study period in the IHG group (P < 0.05). No significant changes in central and peripheral BP and AIx were observed in the CON group.


These results suggest that IHG training could reduce central and peripheral BP and wave reflections in East Asian non-medicated middle-aged and older adults.


Handgrip training Blood pressure Augmentation index Non-pharmacological therapy Cardiovascular disease 



The authors would like to thank Mr. Hiroyuki Hatakeyama for technical assistance with the experiments.


There are no funding sources for the present study.

Compliance with ethical standards

Conflict of interest

The authors have no conflict of interest to declare.

Statement of human and animal rights

This study was approved by the Ethics Committee of Nippon Sport Science University.

Informed consent

Informed consent was obtained from all participants.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Exercise PhysiologyNippon Sport Science UniversityTokyoJapan
  2. 2.Center for Fundamental EducationTeikyo University of ScienceTokyoJapan

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