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Association between dietary nutrient intake and sarcopenia in the SarcoPhAge study

  • Charlotte BeaudartEmail author
  • Médéa Locquet
  • Mathilde Touvier
  • Jean-Yves Reginster
  • Olivier Bruyère
Original Paper

Abstract

Background

It has been suggested that a balanced nutritional intake may be useful in preventing or even reversing sarcopenia.

Aim

To describe cross-sectional associations between dietary nutrient intake and sarcopenia.

Methods

Subjects recruited from the SarcoPhAge study population completed a food frequency questionnaire. The micronutrient and macronutrient intake was evaluated in both sarcopenic and non-sarcopenic participants. The Nutritional Belgian Recommendations of 2016 were used, i.e., adequate intake and estimated average requirement (EAR). For micronutrients, the prevalence of insufficient intake was estimated as the proportion of subjects whose intake was below the EAR.

Results

A total of 331 subjects (mean age of 74.8 ± 5.9 years, 58.9% women) had complete data and were included in this study. Among them, 51 were diagnosed with sarcopenia (15.4%). In the fully adjusted model, analyses revealed that sarcopenic subjects consumed significantly lower amounts of two macronutrients (proteins, lipids) and five micronutrients (potassium, magnesium, phosphorus, iron, and vitamin K) than non-sarcopenic subjects (all p values < 0.005). A significantly increased prevalence of insufficiency was found for sarcopenic subjects compared to non-sarcopenic subjects for potassium, magnesium, iron, calcium and vitamins E and C (all p values < 0.005). The prevalence of sarcopenic subjects who were also below the Nutritional Belgian Recommendations for protein and lipids was significantly higher than that of non-sarcopenic subjects.

Discussion and conclusions

Sarcopenic subjects seem to consume significantly reduced amounts of many micronutrients and macronutrients compared to non-sarcopenic subjects. These results suggest that a poorly balanced diet may be associated with sarcopenia and poor musculoskeletal health, although prospective studies are needed to confirm these findings.

Keywords

Sarcopenia Micronutrient Macronutrient Nutrition Diet Muscle health 

Notes

Acknowledgements

We would first thank all participants of the SarcoPhAge study for the time they dedicated in our research and for their fidelity over the years. We would like to acknowledge Pr. Michèle Guillaume, head of the Department of Public Health of the University of Liège for her help and support in designing our Food Frequency Questionnaire. Moreover, we thank Nathalie Arnault, biostatistician from the «Equipe de Recherche en Epidémiologie Nutritionnelle (EREN, UMR U1153 Inserm/U1125 Inra/Cnam/Universités Paris 5, 7 et 13, Centre de Recherche en Epidémiologie et Statistiques Sorbonne Paris Cité (CRESS)» for their support in analysing results of the Food Frequency Questionnaire.

Funding

CB and ML are supported by a fellowship from the FNRS (Fonds National de la Recherche Scientifique de Belgique—FRSFNRS—http://www.frs-fnrs.be).

Compliance with ethical standards

Conflict of interest

Authors declare that they have no conflicts of interest.

Ethical approval

All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee as well as with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Supplementary material

40520_2019_1186_MOESM1_ESM.pdf (270 kb)
Supplementary material 1 (PDF 270 kb)
40520_2019_1186_MOESM2_ESM.docx (13 kb)
Supplementary material 2 (DOCX 13 kb)

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Public Health, Epidemiology and Health EconomicsUniversity of LiègeLiègeBelgium
  2. 2.WHO Collaborating Centre for Public Health Aspects of Musculo-Skeletal Health and AgingLiègeBelgium
  3. 3.Equipe de Recherche en Epidémiologie Nutritionnelle (EREN, UMR U1153 Inserm/U1125 Inra/Cnam/Universités Paris 5, 7 et 13, Centre de Recherche en Epidémiologie et Statistiques Sorbonne Paris Cité (CRESS)ParisFrance

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