Aging Clinical and Experimental Research

, Volume 30, Issue 5, pp 413–418 | Cite as

Quality of life assessment in musculo-skeletal health

  • Charlotte BeaudartEmail author
  • Emmanuel Biver
  • Olivier Bruyère
  • Cyrus Cooper
  • Nasser Al-Daghri
  • Jean-Yves Reginster
  • René Rizzoli


Musculoskeletal disorders affect morbidity, quality of life and mortality, and represent an increasing economic and societal burden in the context of population aging and increased life expectancy. Improvement of quality of life should be one of the priorities of any interventions to prevent and treat musculoskeletal disorders in the ageing population. Two main approaches, namely generic and disease-specific instruments, can be applied to measure health-related quality of life. Among the generic tools available in scientific literature, the short form 36 questionnaire (SF-36) and the Euroqol five item questionnaire (EQ-5D) are two of the most popular questionnaires used to quantify the health related quality of life in people with musculoskeletal disorders. However, because generic tools may not always be able to detect subtle effects of a specific condition on quality of life, a specific tool is highly valuable. Specific tools improve the ability to clinically characterize quality of life in subjects with a specific musculoskeletal disorder, as well as the capacity to assess changes over time in the QoL of these subjects. The recent development of specific tools should help to validate preventive and therapeutic interventions in this field.


Quality of life Musculo-skeletal health Sarcopenia Osteoporosis Osteoarthritis Frailty 



We thank the Prince Mutaib Bin Abdullah Chair for Biomarkers of Osteoporosis and Deanship of Scientific Research, King Saud University for their support.

Compliance with ethical standards

Conflict of interest

Charlotte Beaudart, Olivier Bruyère and Jean-Yves Reginster are the shareholders of SarQoL® sprl. Others authors have no relevant competing interests to declare.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

For this type of study informed consent is not required.


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© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Department of Public Health, Epidemiology and Health EconomicsUniversity of Liège, Quartier HôpitalLiègeBelgium
  2. 2.Division of Bone Diseases, Faculty of MedicineGeneva University HospitalsGeneva 14Switzerland
  3. 3.MRC Lifecourse Epidemiology UnitUniversity of SouthamptonSouthamptonUK
  4. 4.NIHR Musculoskeletal Biomedical Research UnitUniversity of OxfordOxfordUK
  5. 5.Prince Mutaib Chair for Biomarkers of Osteoporosis, Biochemistry Department, College of ScienceKing Saud UniversityRiyadhSaudi Arabia
  6. 6.Director of the Bone, Cartilage and Muscle Metabolism Unit and Chair of the Department of Public Health SciencesCHU LiègeLiègeBelgium

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