Vitamin D deficiency in relation to general and abdominal obesity among high educated adults
To assess the association of vitamin D deficiency with general and abdominal obesity among high educated Iranian adults.
Current cross-sectional study was done on 500 Iranian professors aged 35 years or more. Complete data on general and abdominal obesity as well as serum 25(OH)D concentrations were available for 352 persons. Obesity was considered as body mass index ≥ 30, and abdominal obesity as waist circumference ≥ 80 cm for women and ≥ 94 cm for men. Furthermore, vitamin D deficiency was defined as serum 25(OH)D < 30 ng/ml.
Mean age of study population was 53.03 ± 7.15 years. Compared with those in the first quartile of serum 25(OH)D, participants in the fourth quartile were less likely to be generally obese (OR 0.46, 65% CI 0.22–0.99). Such finding was also seen even after taking potential confounders into account. Furthermore, we found an inverse association between serum 25(OH)D and abdominal obesity in fully adjusted model (OR 0.44, 95% CI 0.22–0.86). In addition, a significant positive association was found between vitamin D deficiency and obesity; such that after controlling for potential confounders, participants with vitamin D deficiency had 2.16 and 2.04 times greater odds for having general (OR 2.16, 95% CI 1.05–4.45) and abdominal obesity (OR 2.04, 95% CI 1.16–3.60), respectively, than those with normal levels of vitamin D.
Serum 25(OH)D concentrations were inversely associated with general and abdominal obesity. In addition, vitamin D deficiency was positively associated with both general and abdominal obesity.
Level of evidence
Level V, cross-sectional descriptive study.
KeywordsAnthropometry Obesity Vitamin D Abdominal obesity
Authors appreciate the valuable assistance of all subjects. We also would like to thank the authorities of Health Center of Tarbiat Modares University, Tehran, Iran, for their cooperation.
This study was supported by Health Center of Tarbiat Modares University, Tehran, Iran.
Compliance with ethical standards
Conflict of interest
Authors declared no personal or financial conflicts of interest.
All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all subjects included in the study.
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