Laparoscopic sleeve gastrectomy in adolescents with or without syndromic obesity: two years follow-up

  • Angelo Iossa
  • Francesco De Peppo
  • Romina Caccamo
  • Brad Michael Watkins
  • Francesca Abbatini
  • Emanuela Ceriati
  • Gianfranco SilecchiaEmail author
Original Article



Childhood obesity is an emerging health problem. Surgical treatment of obese adolescents, particularly those affected by congenital syndrome, represents a controversial issue. The aim of this multicenter study was to retrospectively assess the results of laparoscopic sleeve gastrectomy (LSG) in a cohort of adolescents affected by morbid obesity, with or without congenital syndromes.

Materials and methods

Forty-one obese (BMI 49 ± 6 kg/m2) adolescents with mean age of 16 ± 3 years (58.5% with previous intragastric balloon failure), and subjected to LSG, were retrospectively evaluated for complications rate, % excess weight loss (%EWL), and inhibition of co-morbidities after 2 years of follow-up.


All the operations were completed laparoscopically and no intra-operative complications were recorded. No mortality was recorded while peri- or post-operative complications only occurred in two patients (4.9%). The EWL% at 6, 12, and 24 months were 42.3, 58.3, and 59.4, respectively. %EWL was comparable (p = 0.7) between non-syndromic and syndromic obese adolescents at 24 months. Conversely patients with previous intragastric balloon surgery had a significant lower EWL (%) at 24 month (p < 0.01). Moreover, at the same time point, co-morbidity resolution rate was 78.2% while improvement rate was 57.6%. Specifically, remission rate of type 2 diabetes (T2DM), hypertension and obstructive sleep apnea (OSA) were 71, 75 and 61%, respectively.


LSG is advantageous in the treatment of morbidly obese juveniles concerning safety, weight loss and co-morbidity control and at same time presenting, a possible effective therapeutic option for patients affected by congenital syndrome.


Bariatric surgery in teenagers Childhood obesity Sleeve gastrectomy Adolescents Syndromic obesity Surgical treatment 


Compliance with ethical standards

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Angelo Iossa
    • 1
  • Francesco De Peppo
    • 2
  • Romina Caccamo
    • 2
  • Brad Michael Watkins
    • 3
  • Francesca Abbatini
    • 1
  • Emanuela Ceriati
    • 2
  • Gianfranco Silecchia
    • 1
    Email author
  1. 1.Department of Medical-Surgical Sciences and Biotechnologies, Division of General Surgery and Bariatric Centre of Excellence“La Sapienza”, University of RomeRomeItaly
  2. 2.Department of Paediatric SurgeryHospital Bambino Gesù”Palidoro (Rm)Italy
  3. 3.Division of General Surgery and Weight LOSS Center, West Chester HospitalUniversity of CincinnatiCincinnatiUSA

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