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Periodontal Disease and Systemic Interactions (Periodontal Medicine): Current Epidemiological Evidence

  • James D. BeckEmail author
  • Kamaira H. Philips
  • Sanjana S. Rao
Host Parasite Interactions in Periodontal Disease (C Genco and D Kinane, Section Editors)
  • 8 Downloads
Part of the following topical collections:
  1. Topical Collection on Host Parasite Interactions in Periodontal Disease
  2. Topical Collection on Host Parasite Interactions in Periodontal Disease

Abstract

Purpose of Review

To review recent literature on the effects of periodontal diseases on type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) with emphasis on the contributions of Dr. Robert Genco.

Recent Findings

Numbers of missing teeth are positively related to levels of infection and inflammation. Most studies find a positive relationship between periodontitis and incident CVD and T2DM and the ability of periodontal treatment to reduce CVD risk factors and HbA1C levels, but controversy due to negative findings remains.

Summary

Recent finding that tooth loss is related to levels of inflammation is important as it provides clues to how tooth loss is related to systemic diseases. New studies involving microorganisms and host response are important, as they underlie clinical signs. Basic problems, such as periodontal case definitions, type of treatments, timing of treatment, and follow-up times need to be addressed in order to reduce inconsistent findings in epidemiologic studies and clinical trials.

Keywords

Periodontal disease Type 2 diabetes mellitus Atherosclerosis Cardiovascular disease Epidemiology 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • James D. Beck
    • 1
    Email author
  • Kamaira H. Philips
    • 2
  • Sanjana S. Rao
    • 2
  1. 1.Division of Comprehensive Oral Health/Periodontology, Adams School of DentistryUniversity of North CarolinaChapel HillUSA
  2. 2.Division of Oral and Craniofacial Health Sciences, Adams School of DentistryUniversity of North CarolinaChapel HillUSA

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