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Current Oral Health Reports

, Volume 4, Issue 4, pp 319–329 | Cite as

Revascularization of Immature Necrotic Teeth

  • Nikita B. RuparelEmail author
  • Vanessa Chrepa
  • Jennifer L. Gibbs
Dental Stem Cells in Tissue Regeneration (F Setzer, Section Editor)
  • 137 Downloads
Part of the following topical collections:
  1. Topical Collection on Dental Stem Cells in Tissue Regeneration

Abstract

Purpose of Review

The objective of this review is to provide an overview of the past and present advancements in regenerative endodontics.

Recent Findings

Available literature clearly demonstrates high-clinical success of regenerative endodontic procedures (REP). Several recommendations made by the American Association of Endodontists (AAE) with regard to REP protocols are based on recent work demonstrating these as stem cell-based therapies. This review summarizes the role of stem cells and therefore the rationale for the currently recommended guidelines.

Summary

Clinical success of REP lies between 80 and 100% with root development observed in a significant number of treated cases. These procedures provide a unique advantage of continued root growth despite premature pulp necrosis in immature teeth. Research in the field of stem cell biology has greatly increased our understanding of tissue engineering in endodontics. Overall, REPs appear to be a viable treatment option for immature teeth with pulp necrosis.

Keywords

Regenerative endodontics Root development Immature necrotic teeth Root canal Revascularization Stem cells 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflicts of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

Papers of particular interest, published recently, have been highlighted as: •• Of major importance

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Nikita B. Ruparel
    • 1
    Email author
  • Vanessa Chrepa
    • 2
  • Jennifer L. Gibbs
    • 3
  1. 1.Department of EndodonticsUniversity of Texas Health Science at San AntonioSan AntonioUSA
  2. 2.Department of EndodonticsUniversity of Washington School of DentistrySeattleUSA
  3. 3.Department of EndodonticsNew York UniversityNew YorkUSA

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