The Utility of Chewing Gum in Treating White Spot Lesions
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White spot lesions (WSL) are early non-cavitated carious lesions where the subsurface mineral loss has produced changes in the optical properties of the enamel. These lesions are visibly detectable as the loss of translucency results in a white appearance of the enamel surface. WSL can be arrested or reversed if the cariogenic challenge is sufficiently controlled or therapeutic agents are applied to promote enamel remineralization. Sugar-free chewing gum has been shown to promote the remineralization of enamel subsurface lesions in situ. Recently, manufacturers have been adding bioavailable calcium and fluoride in various forms to enhance anticariogenic and remineralization potential. This review describes the use of chewing gum which includes bioavailable agents for remineralization of WSL. Chewing gum is a noninvasive clinical approach for WSL remineralization, but further clinical studies are needed. Providing evidence on the effectiveness of these new noninvasive treatment approaches using technologies such as optical coherence tomography remains a priority in dental research.
KeywordsChewing gum Enamel OCT Remineralization White spot lesion
This study was supported by a Grant-in-Aid for Scientific Research (No.25462946) from the Japan Society for the Promotion of Science (JSPS) and a Research Grant for Longevity Sciences (21A-8) from the Ministry of Health, Labor and Welfare.
Compliance with Ethical Standards
Conflict of Interest
Yuichi Kitasako, Alireza Sadr, Yasushi Shimada, Yasunori Sumi, and Junji Tagami declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
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