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Overweight and Obesity in Children with Autism Spectrum Disorder (ASD): a Critical Review Investigating the Etiology, Development, and Maintenance of this Relationship

  • Brittany E. Matheson
  • Jennifer M. Douglas
Review Paper

Abstract

Pediatric obesity is associated with negative health and psychosocial consequences. However, obesity may not uniformly affect all populations. Limited research has investigated the factors that contribute to the incidence and persistence of overweight and obesity among children with autism spectrum disorder (ASD). This review systematically examined the prevalence rate of overweight and obesity among children with ASD. The majority of studies suggest that children with ASD may be at a greater risk for excess weight gain compared to typically developing peers. Additionally, this review investigated potential contributing factors to the etiology and maintenance of obesity within this population. Research should continue to investigate excess weight gain in this population in order to adapt weight loss interventions for children with ASD.

Keywords

Autism spectrum disorder Pediatric obesity 

Notes

Compliance with Ethical Standards

Funding

The authors have no funding sources to disclose.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Conflict of Interest

The authors declare that they have no conflicts of interest.

References

  1. ABA Therapists. (2003). Reinforcement and ABA therapy. Applied Behavior Analysis Training Guide. Retrieved May 10, 2016 from http://abatherapists.com/reinforcement-and-aba-therapy/.
  2. Abdul-Rasoul, M. M. (2012). Obesity in children and adolescents in Gulf countries: facts and solutions. Avances en Diabetologia, 28(3), 64–69.CrossRefGoogle Scholar
  3. Agras, W. S., Hammer, L. D., McNicholas, F., & Kraemer, H. C. (2004). Risk factors for childhood overweight: a prospective study from birth to 9.5 years. The Journal of Pediatrics, 145(1), 20–25.CrossRefPubMedGoogle Scholar
  4. Alasfoor, D., & Mohammed, A. J. (2009). Implications of the use of the new WHO growth charts on the interpretation of malnutrition and obesity in infants and young children in Oman. Eastern Mediterranean Health Journal, 15(4), 890–898.PubMedGoogle Scholar
  5. Al-Farsi, Y. M., Al-Sharbati, M. M., Waly, M. I., Al-Farsi, O. A., Al Shafaee, M. A., & Deth, R. C. (2011). Malnutrition among preschool-aged autistic children in Oman. Research in Autism Spectrum Disorders, 5(4), 1549–1552.CrossRefGoogle Scholar
  6. Almandil, N. B., Liu, Y., Murray, M. L., Besag, F. M., Aitchison, K. J., & Wong, I. C. (2013). Weight gain and other metabolic adverse effects associated with atypical antipsychotic treatment of children and adolescents: a systematic review and meta-analysis. Pediatric Drugs, 15(2), 139–150.CrossRefPubMedGoogle Scholar
  7. American Academy of Pediatrics. (2001). Clinical practice guideline: treatment of the school- aged child with attention-deficit/hyperactivity disorder. Pediatrics, 108(4), 1033–1044.CrossRefGoogle Scholar
  8. Anglesea, M. M., Hoch, H., & Taylor, B. A. (2008). Reducing rapid eating in teenagers with autism: use of a pager prompt. Journal of Applied Behavior Analysis, 41(1), 107–111.PubMedCentralCrossRefPubMedGoogle Scholar
  9. Attlee, A., Kassem, H., Hashim, M., & Obaid, R. S. (2015). Physical status and feeding behavior of children with autism. The Indian Journal of Pediatrics, 82(8), 682–687.CrossRefPubMedGoogle Scholar
  10. Bak, M., Fransen, A., Janssen, J., van Os, J., & Drukker, M. (2014). Almost all antipsychotics result in weight gain: a meta-analysis. PloS One, 9(4), e94112.PubMedCentralCrossRefPubMedGoogle Scholar
  11. Bandini, L. G., Anderson, S. E., Curtin, C., Cermak, S., Evans, E. W., Scampini, R., et al. (2010). Food selectivity in children with autism spectrum disorders and typically developing children. The Journal of Pediatrics, 157(2), 259–264.PubMedCentralCrossRefPubMedGoogle Scholar
  12. Barnhill, K., Gutierrez, A., Ghossainy, M., Marediya, Z., Marti, C. N., & Hewitson, L. (2017). Growth status of children with autism spectrum disorder: a case–control study. Journal of Human Nutrition and Dietetics, 30(1), 59–65.CrossRefPubMedGoogle Scholar
  13. Bicer, A. H., & Alsaffar, A. A. (2013). Body mass index, dietary intake and feeding problems of Turkish children with autism spectrum disorder (ASD). Research in Developmental Disabilities, 34(11), 3978–3987.CrossRefPubMedGoogle Scholar
  14. Bochukova, E. G., Huang, N. I., Keogh, J., Henning, E., Purmann, C., Blaszczyk, K., Saeed, S., Hamilton-Shield, J., Clayton-Smith, J., O’Rahilly, S., & Hurles, M. E. (2010). Large, rare chromosomal deletions associated with severe early-onset obesity. Nature, 463(7281), 666–670.CrossRefPubMedGoogle Scholar
  15. Boutelle, K. N., Hannan, P., Fulkerson, J. A., Crow, S. J., & Stice, E. (2010). Obesity as a prospective predictor of depression in adolescent females. Health Psychology, 29(3), 293–298.PubMedCentralCrossRefPubMedGoogle Scholar
  16. Boutelle, K. N., Cafri, G., & Crow, S. J. (2011). Parent-only treatment for childhood obesity: a randomized controlled trial. Obesity, 19(3), 574–580.CrossRefPubMedGoogle Scholar
  17. Boutelle, K. N., Braden, A., Douglas, J. M., Rhee, K. E., Strong, D., Rock, C. L., Wilfley, D. E., Epstein, L., & Crow, S. J. (2015a). Design of the FRESH study: a randomized controlled trial of a parent-only and parent–child family-based treatment for childhood obesity. Contemporary Clinical Trials, 45, 364–370.PubMedCentralCrossRefPubMedGoogle Scholar
  18. Boutelle, K. N., Liang, J., Knatz, S., Matheson, B., Risbrough, V., Strong, D., Rhee, K. E., Craske, M. G., Zucker, N., & Bouton, M. E. (2015b). Design and implementation of a study evaluating extinction processes to food cues in obese children: the Intervention for Regulations of Cues Trial (iROC). Contemporary Clinical Trials, 40, 95–104.CrossRefPubMedGoogle Scholar
  19. Brion, M. J., Zeegers, M., Jaddoe, V., Verhulst, F., Tiemeier, H., Lawlor, D. A., & Smith, G. D. (2011). Maternal pre-pregnancy overweight and child cognition and behavior: exploring intrauterine effects in two pregnancy cohorts. Pediatrics, 127(1), e202.CrossRefPubMedGoogle Scholar
  20. Broder-Fingert, S., Brazauskas, K., Lindgren, K., Iannuzzi, D., & Van Cleave, J. (2014). Prevalence of overweight and obesity in a large clinical sample of children with autism. Academic Pediatrics, 14(4), 408–414.CrossRefPubMedGoogle Scholar
  21. Butryn, M. L., Webb, V., & Wadden, T. A. (2011). Behavioral treatment of obesity. The Psychiatric Clinics of North America, 34(4), 841–859.PubMedCentralCrossRefPubMedGoogle Scholar
  22. Calarge, C. A., Acion, L., Kuperman, S., Tansey, M., & Schlechte, J. A. (2009). Weight gain and metabolic abnormalities during extended risperidone treatment in children and adolescents. Journal of Child and Adolescent Psychopharmacology, 19(2), 101–109.PubMedCentralCrossRefPubMedGoogle Scholar
  23. Cascio, C. J., Foss-Feig, J. H., Heacock, J. L., Newsom, C. R., Cowan, R. L., Benningfield, M. M., Rogers, B. P., & Cao, A. (2012). Response of neural reward regions to food cues in autism spectrum disorders. Journal of Neurodevelopmental Disorders, 4(1), 9–19.PubMedCentralCrossRefPubMedGoogle Scholar
  24. Center for Autism Research. (2014). Applied behavioral analysis (ABA). CAR Autism Roadmap. Retrieved June 26, 2016 from https://www.carautismroadmap.org/applied- behavior-analysis-aba/.
  25. Cermak, S. A., Curtin, C., & Bandini, L. G. (2010). Food selectivity and sensory sensitivity in children with autism spectrum disorders. Journal of the American Dietetic Association, 110(2), 238–246.PubMedCentralCrossRefPubMedGoogle Scholar
  26. Charach, A., Ickowicz, A., & Schachar, R. (2004). Stimulant treatment over five years: adherence, effectiveness, and adverse effects. Journal of the American Academy of Child & Adolescent Psychiatry, 43(5), 559–567.CrossRefGoogle Scholar
  27. Chen, A. Y., Kim, S. E., Houtrow, A. J., & Newacheck, P. W. (2010). Prevalence of obesity among children with chronic conditions. Obesity, 18(1), 210–213.CrossRefPubMedGoogle Scholar
  28. Cormier, E. (2008). Attention deficit/hyperactivity disorder: a review and update. Journal of Pediatric Nursing, 23(5), 345–357.CrossRefPubMedGoogle Scholar
  29. Corvey, K., Menear, K. S., Preskitt, J., Goldfarb, S., & Menachemi, N. (2016). Obesity, physical activity and sedentary behaviors in children with an autism spectrum disorder. Maternal and Child Health Journal, 20(2), 466–476.CrossRefPubMedGoogle Scholar
  30. Croen, L. A., Zerbo, O., Qian, Y., Massolo, M. L., Rich, S., Sidney, S., & Kripke, C. (2015). The health status of adults on the autism spectrum. Autism, 19(7), 814–823.CrossRefPubMedGoogle Scholar
  31. Curtin, C., Bandini, L. G., Perrin, E. C., Tybor, D. J., & Must, A. (2005). Prevalence of overweight in children and adolescents with attention deficit hyperactivity disorder and autism spectrum disorders: a chart review. BioMed Central Pediatrics, 5(1), 48–54.PubMedCentralPubMedGoogle Scholar
  32. Curtin, C., Anderson, S. E., Must, A., & Bandini, L. (2010). The prevalence of obesity in children with autism: a secondary data analysis using nationally representative data from the National Survey of Children’s Health. BioMed Central Pediatrics, 10(1), 11–15.PubMedCentralCrossRefPubMedGoogle Scholar
  33. Demb, H., Valicenti-McDermott, M., Navarro, A., & Ayoob, K. E. (2011). The effect of long-term use of risperidone on body weight of children with an autism spectrum disorder. Journal of Clinical Psychopharmacology, 31, 669–670.CrossRefPubMedGoogle Scholar
  34. DMNSY Developmental. (2014). Prevalence of autism spectrum disorder among children aged 8 years—autism and developmental disabilities monitoring network, 11 sites, United States, 2010. Morbidity and Mortality Weekly Report. Surveillance summaries (Washington, DC: 2002), 63(2), 1.Google Scholar
  35. Egan, A. M., Dreyer, M. L., Odar, C. C., Beckwith, M., & Garrison, C. B. (2013). Obesity in young children with autism spectrum disorders: prevalence and associated factors. Childhood Obesity, 9(2), 125–131.CrossRefPubMedGoogle Scholar
  36. Epstein, L. H., Valoski, A., Wing, R. R., & McCurley, J. (1994). Ten-year outcomes of behavioral family-based treatment for childhood obesity. Health Psychology, 13(5), 373–383.CrossRefPubMedGoogle Scholar
  37. Epstein, L. H., Paluch, R. A., Roemmich, J. N., & Beecher, M. D. (2007). Family-based obesity treatment, then and now: twenty-five years of pediatric obesity treatment. Health Psychology, 26(4), 381–391.PubMedCentralCrossRefPubMedGoogle Scholar
  38. Evans, E. W., Must, A., Anderson, S. E., Curtin, C., Scampini, R., Maslin, M., & Bandini, L. (2012). Dietary patterns and body mass index in children with autism and typically developing children. Research in Autism Spectrum Disorders, 6(1), 399–405.PubMedCentralCrossRefPubMedGoogle Scholar
  39. Faith, M. S., Scanlon, K. S., Birch, L. L., Francis, L. A., & Sherry, B. (2004). Parent-child feeding strategies and their relationships to child eating and weight status. Obesity Research, 12(11), 1711–1722.CrossRefPubMedGoogle Scholar
  40. Fallon, E. M., Tanofsky-Kraff, M., Norman, A. C., McDuffie, J. R., Taylor, E. D., Cohen, M. L., Young-Hyman, D., Keil, M., Kolotkin, R. L., & Yanovski, J. A. (2005). Health-related quality of life in overweight and nonoverweight black and white adolescents. The Journal of Pediatrics, 147(4), 443–450.PubMedCentralCrossRefPubMedGoogle Scholar
  41. Farooqi, I. S. (2005). Genetic and hereditary aspects of childhood obesity. Best Practice & Research Clinical Endocrinology & Metabolism, 19(3), 359–374.CrossRefGoogle Scholar
  42. Ferguson, J. M. (2001). SSRI antidepressant medications: adverse effects and tolerability. Primary Care Companion Journal Clinical Psychiatry, 3(1), 22–27.CrossRefGoogle Scholar
  43. Fischbach, G. D., & Lord, C. (2010). The Simons Simplex Collection: a resource for identification of autism genetic risk factors. Neuron, 68(2), 192–195.CrossRefPubMedGoogle Scholar
  44. Fischbach, B. V., Trout, K. L., Lewis, J., Luis, C. A., & Sika, M. (2005). WAGR syndrome: a clinical review of 54 cases. Pediatrics, 116(4), 984–988.CrossRefPubMedGoogle Scholar
  45. Foster, G. D., Makris, A. P., & Bailer, B. A. (2005). Behavioral treatment of obesity. The American Journal of Clinical Nutrition, 82(1), 230S–235S.PubMedGoogle Scholar
  46. Fournier, K. A., Hass, C. J., Naik, S. K., Lodha, N., & Cauraugh, J. H. (2010). Motor coordination in autism spectrum disorders: a synthesis and meta-analysis. Journal of Autism and Developmental Disorders, 40(10), 1227–1240.CrossRefPubMedGoogle Scholar
  47. Freedman, D. S., Mei, Z., Srinivasan, S. R., Berenson, G. S., & Dietz, W. H. (2007). Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. The Journal of Pediatrics, 150(1), 12–17.CrossRefPubMedGoogle Scholar
  48. Gaugler, T., Klei, L., Sanders, S. J., Bodea, C. A., Goldberg, A. P., Lee, A. B., & Ripke, S. (2014). Most genetic risk for autism resides with common variation. Nature Genetics, 46(8), 881–885.PubMedCentralCrossRefPubMedGoogle Scholar
  49. Gibson, L. Y., Byrne, S. M., Davis, E. A., & Blair, E. (2007). The role of family and maternal factors in childhood obesity. Medical Journal of Australia, 186(11), 591–595.PubMedGoogle Scholar
  50. Gillette, M. L. D., Borner, K. B., Nadler, C. B., Poppert, K. M., Stough, C. O., Romine, R. S., & Davis, A. M. (2015). Prevalence and health correlates of overweight and obesity in children with autism spectrum disorder. Journal of Developmental & Behavioral Pediatrics, 36(7), 489–496.Google Scholar
  51. Glasofer, D. R., Tanofsky-Kraff, M., Eddy, K. T., Yanovski, S. Z., Theim, K. R., Mirch, M. C., Ghorbani, S., & Yanovski, J. A. (2007). Binge eating in overweight treatment-seeking adolescents. Journal of Pediatric Psychology, 32(1), 95–105.CrossRefPubMedGoogle Scholar
  52. Granich, J., Lin, A., Hunt, A., Wray, J., Dass, A., & Whitehouse, A. J. (2016). Obesity and associated factors in youth with an autism spectrum disorder. Autism, 20(8), 916–926.CrossRefPubMedGoogle Scholar
  53. Green, D., Charman, T., Pickles, A., Chandler, S., Loucas, T., Simonoff, E., & Baird, G. (2009). Impairment in movement skills of children with autistic spectrum disorders. Developmental Medicine & Child Neurology, 51(4), 311–316.CrossRefGoogle Scholar
  54. Hallmayer, J., Cleveland, S., Torres, A., Phillips, J., Cohen, B., Torigoe, T., & Lotspeich, L. (2011). Genetic heritability and shared environmental factors among twin pairs with autism. Archives of General Psychiatry, 68(11), 1095–1102.PubMedCentralCrossRefPubMedGoogle Scholar
  55. Hannon, T. S., Rao, G., & Arslanian, S. A. (2005). Childhood obesity and type 2 diabetes mellitus. Pediatrics, 116(2), 473–480.CrossRefPubMedGoogle Scholar
  56. Haworth, C., Plomin, R., Carnell, S., & Wardle, J. (2008). Childhood obesity: genetic and environmental overlap with normal-range BMI. Obesity, 16(7), 1585–1590.CrossRefPubMedGoogle Scholar
  57. Hellings, J. A., Zarcone, J. R., Crandall, K., Wallace, D., & Schroeder, S. R. (2001). Weight gain in a controlled study of risperidone in children, adolescents and adults with mental retardation and autism. Journal of Child and Adolescent Psychopharmacology, 11(3), 229–238.CrossRefPubMedGoogle Scholar
  58. Hill, E. L. (2004). Evaluating the theory of executive dysfunction in autism. Developmental Review, 24(2), 189–233.CrossRefGoogle Scholar
  59. Hill, A. P., Zuckerman, K. E., & Fombonne, E. (2015). Obesity and autism. Pediatrics, 136(6), 1051–1061.PubMedCentralCrossRefPubMedGoogle Scholar
  60. Ho, H. H., Eaves, L. C., & Peabody, D. (1997). Nutrient intake and obesity in children with autism. Focus on Autism and Other Developmental Disabilities, 12(3), 187–192.CrossRefGoogle Scholar
  61. Hollander, E., Phillips, A., Chaplin, W., Zagursky, K., Novotny, S., Wasserman, S., & Iyengar, R. (2005). A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism. Neuropsychopharmacology, 30(3), 582–589.CrossRefPubMedGoogle Scholar
  62. Horvath, K., & Perman, J. A. (2002). Autism and gastrointestinal symptoms. Current Gastroenterology Reports, 4(3), 251–258.CrossRefPubMedGoogle Scholar
  63. Hyman, S. L., Stewart, P. A., Schmidt, B., Lemcke, N., Foley, J. T., Peck, R., & James, S. J. (2012). Nutrient intake from food in children with autism. Pediatrics, 130(Supplement 2), S145–S153.PubMedCentralCrossRefPubMedGoogle Scholar
  64. Jansen, A. (1998). A learning model of binge eating: cue reactivity and cue exposure. Behaviour Research and Therapy, 36(3), 257–272.CrossRefPubMedGoogle Scholar
  65. Janssen Pharmaceuticals. (2014). Risperdal® (risperidone). Retrieved May 8, 2016 from http://www.janssen.com/us/sites/www_janssen_com_usa/files/products-documents/risperdal.pdf
  66. Jerrell, J. M. (2010). Neuroendocrine-related adverse events associated with antidepressant treatment in children and adolescents. CNS Neuroscience & Therapeutics, 16(2), 83–90.CrossRefGoogle Scholar
  67. Kelly, A.N. (2008). Common misconceptions about applied behavior analysis. Behaviorbabe. Retrieved May 10, 2016 from http://www.behaviorbabe.com/commonmisconceptions.htm.
  68. Kirk, S. F., Penney, T. L., & McHugh, T. L. (2010). Characterizing the obesogenic environment: the state of the evidence with directions for future research. Obesity Reviews, 11(2), 109–117.CrossRefPubMedGoogle Scholar
  69. Kodak, T., & Piazza, C. C. (2008). Assessment and behavioral treatment of feeding and sleeping disorders in children with autism spectrum disorders. Child and Adolescent Psychiatric Clinics of North America, 17(4), 887-905.Google Scholar
  70. Krakowiak, P., Walker, C. K., Bremer, A. A., Baker, A. S., Ozonoff, S., Hansen, R. L., & Hertz-Picciotto, I. (2012). Maternal metabolic conditions and risk for autism and other neurodevelopmental disorders. Pediatrics, 129(5), e1121–e1128.PubMedCentralCrossRefPubMedGoogle Scholar
  71. Kral, T. V., & Faith, M. S. (2009). Influences on child eating and weight development from a behavioral genetics perspective. Journal of Pediatric Psychology, 34(6), 596–605.CrossRefPubMedGoogle Scholar
  72. Kral, T. V., Souders, M. C., Tompkins, V. H., Remiker, A. M., Eriksen, W. T., & Pinto-Martin, J. A. (2015). Child eating behaviors and caregiver feeding practices in children with autism spectrum disorders. Public Health Nursing, 32(5), 488–497.CrossRefPubMedGoogle Scholar
  73. Kummer, A., Barbosa, I. G., Rodrigues, D. H., Rocha, N. P., da Silva Rafael, M., Pfeilsticker, L., et al. (2016). Frequency of overweight and obesity in children and adolescents with autism and attention deficit/hyperactivity disorder. Revista Paulista de Pediatria (English Edition), 34(1), 71–77.CrossRefGoogle Scholar
  74. Lawson, L. M., & Foster, L. (2016). Sensory patterns, obesity, and physical activity participation of children with autism spectrum disorder. American Journal of Occupational Therapy, 70(5), 1–8.CrossRefGoogle Scholar
  75. Liang, J., Matheson, B. E., Kaye, W. H., & Boutelle, K. N. (2014). Neurocognitive correlates of obesity and obesity-related behaviors in children and adolescents. International Journal of Obesity, 38(4), 494–506.CrossRefPubMedGoogle Scholar
  76. MacDonald, M., Esposito, P., & Ulrich, D. (2011). The physical activity patterns of children with autism. BioMed Central Research Notes, 4(1), 422–426.PubMedCentralPubMedGoogle Scholar
  77. Malik, V. S., Pan, A., Willett, W. C., & Hu, F. B. (2013). Sugar-sweetened beverages and weight gain in children and adults: a systematic review and meta-analysis. The American Journal of Clinical Nutrition, 98(4), 1084–1102.PubMedCentralCrossRefPubMedGoogle Scholar
  78. Manios, Y., Costarelli, V., Kolotourou, M., Kondakis, K., Tzavara, C., & Moschonis, G. (2007). Prevalence of obesity in preschool Greek children, in relation to parental characteristics and region of residence. BioMed Central Public Health, 7(1), 178–185.PubMedCentralCrossRefPubMedGoogle Scholar
  79. Martins, Y., Young, R. L., & Robson, D. C. (2008). Feeding and eating behaviors in children with autism and typically developing children. Journal of Autism and Developmental Disorders, 38(10), 1878–1887.CrossRefPubMedGoogle Scholar
  80. Matheson, B. E., Camacho, C., Peterson, C. B., Rhee, K. E., Rydell, S. A., Zucker, N. L., & Boutelle, K. N. (2015). The relationship between parent feeding styles and general parenting with loss of control eating in treatment-seeking overweight and obese children. International Journal of Eating Disorders, 48(7), 1047–1055.CrossRefPubMedGoogle Scholar
  81. Matson, J. L., & Boisjoli, J. A. (2009). The token economy for children with intellectual disability and/or autism: A review. Research in Developmental Disabilities, 30(2), 240–248.CrossRefPubMedGoogle Scholar
  82. Mazurek, M. O., Shattuck, P. T., Wagner, M., & Cooper, B. P. (2012). Prevalence and correlates of screen-based media use among youths with autism spectrum disorders. Journal of Autism and Developmental Disorders, 42(8), 1757–1767.PubMedCentralCrossRefPubMedGoogle Scholar
  83. McCoy, S. M., Jakicic, J. M., & Gibbs, B. B. (2016). Comparison of obesity, physical activity, and sedentary behaviors between adolescents with autism spectrum disorders and without. Journal of Autism and Developmental Disorders, 46(7), 2317–2326.CrossRefPubMedGoogle Scholar
  84. McCracken, J. T., McGough, J., Shah, B., Cronin, P., Hong, D., Aman, M. G., Arnold, L. E., Lindsay, R., Nash, P., Hollway, J., & McDougle, C. J. (2002). Risperidone in children with autism and serious behavioral problems. New England Journal of Medicine, 347(5), 314–321.CrossRefPubMedGoogle Scholar
  85. McDougle, C. J., Holmes, J. P., Carlson, D. C., Pelton, G. H., Cohen, D. J., & Price, L. H. (1998). A double-blind, placebo-controlled study of risperidone in adults with autistic disorder and other pervasive developmental disorders. Archives of General Psychiatry, 55(7), 633–641.CrossRefPubMedGoogle Scholar
  86. McDougle, C. J., Kresch, L. E., & Posey, D. J. (2000). Repetitive thoughts and behavior in pervasive developmental disorders: Treatment with serotonin reuptake inhibitors. Journal of Autism and Developmental Disorders, 30(5), 427–435.CrossRefPubMedGoogle Scholar
  87. McDougle, C. J., Scahill, L., Aman, M. G., McCracken, J. T., Tierney, E., Davies, M., Arnold, L. E., & Shah, B. (2005). Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. American Journal of Psychiatry, 162(6), 1142–1148.CrossRefPubMedGoogle Scholar
  88. Memari, A. H., Kordi, R., Ziaee, V., Mirfazeli, F. S., & Setoodeh, M. S. (2012). Weight status in Iranian children with autism spectrum disorders: Investigation of underweight, overweight and obesity. Research in Autism Spectrum Disorders, 6(1), 234–239.CrossRefGoogle Scholar
  89. Musaiger, A. O. (2011). Overweight and obesity in eastern mediterranean region: prevalence and possible causes. Journal of Obesity, 2011, 1–17.CrossRefGoogle Scholar
  90. Must, A., Phillips, S. M., Curtin, C., Anderson, S. E., Maslin, M., Lividini, K., & Bandini, L. G. (2014). Comparison of sedentary behaviors between children with autism spectrum disorders and typically developing children. Autism, 18(4), 376–384.CrossRefPubMedGoogle Scholar
  91. Nadon, G., Feldman, D. E., Dunn, W., & Gisel, E. (2011). Mealtime problems in children with autism spectrum disorder and their typically developing siblings: a comparison study. Autism, 15(1), 98–113.CrossRefPubMedGoogle Scholar
  92. Obrusnikova, I., & Cavalier, A. R. (2011). Perceived barriers and facilitators of participation in after-school physical activity by children with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 23(3), 195–211.CrossRefGoogle Scholar
  93. Ogden, C. L., Lamb, M. M., Carroll, M. D., & Flegal, K. M. (2010). Obesity and socioeconomic status in children and adolescents: United States, 2005–2008. NCHS Data Brief, Number 51. Hyattsville, MD: National Center for Health Statistics.Google Scholar
  94. Ogden, C. L., Carroll, M. D., Kit, B. K., & Flegal, K. M. (2012). Prevalence of obesity and trends in body mass index among US children and adolescents, 1999–2010. The Journal of the American Medical Association, 307(5), 483–490.CrossRefPubMedGoogle Scholar
  95. Ogden, C. L., Carroll, M. D., Kit, B. K., & Flegal, K. M. (2014). Prevalence of childhood and adult obesity in the United States, 2011–2012. The Journal of the American Medical Association, 311(8), 806–814.CrossRefPubMedGoogle Scholar
  96. Pan, C. Y. (2008). Objectively measured physical activity between children with autism spectrum disorders and children without disabilities during inclusive recess settings in Taiwan. Journal of Autism and Developmental Disorders, 38, 1292–1301.CrossRefPubMedGoogle Scholar
  97. Phillips, K. L., Schieve, L. A., Visser, S., Boulet, S., Sharma, A. J., Kogan, M. D., & Yeargin-Allsopp, M. (2014). Prevalence and impact of unhealthy weight in a national sample of US adolescents with autism and other learning and behavioral disabilities. Maternal and Child Health Journal, 18(8), 1964–1975.PubMedCentralCrossRefPubMedGoogle Scholar
  98. Polfuss, M., Johnson, N., Bonis, S. A., Hovis, S. L., Apollon, F., & Sawin, K. J. (2016). Autism spectrum disorder and the child’s weight-related behaviors: a parent’ perspective. Journal of Pediatric Nursing, 31(6), 598–607.CrossRefPubMedGoogle Scholar
  99. Polivy, J., Herman, C. P., & Coelho, J. S. (2008). Caloric restriction in the presence of attractive food cues: external cues, eating, and weight. Physiology & Behavior, 94(5), 729–733.CrossRefGoogle Scholar
  100. Pringle B. A., Colpe L. J., Blumberg S. J., Avila R. M., & Kogan M. D. (2012). Diagnostic history and treatment of school-aged children with autism spectrum disorder and special health care needs. NCHS Data Brief, Number 97. Hyattsville, MD: National Center for Health Statistics.Google Scholar
  101. Provost, B., Crowe, T. K., Osbourn, P. L., McClain, C., & Skipper, B. J. (2010). Mealtime behaviors of preschool children: comparison of children with autism spectrum disorder and children with typical development. Physical & Occupational Therapy in Pediatrics, 30(3), 220–233.CrossRefGoogle Scholar
  102. Rajendran, G., & Mitchell, P. (2007). Cognitive theories of autism. Developmental Review, 27(2), 224–260.CrossRefGoogle Scholar
  103. Reekie, J., Hosking, S. P. M., Prakash, C., Kao, K. T., Juonala, M., & Sabin, M. A. (2015). The effect of antidepressants and antipsychotics on weight gain in children and adolescents. Obesity Reviews, 16(7), 566–580.CrossRefPubMedGoogle Scholar
  104. Reilly, J. J., & Kelly, J. (2011). Long-term impact of overweight and obesity in childhood and adolescence on morbidity and premature mortality in adulthood: systematic review. International Journal of Obesity, 35(7), 891–898.CrossRefPubMedGoogle Scholar
  105. Reilly, J. J., Methven, E., McDowell, Z. C., Hacking, B., Alexander, D., Stewart, L., & Kelnar, C. J. (2003). Health consequences of obesity. Archives of Disease in Childhood, 88(9), 748–752.PubMedCentralCrossRefPubMedGoogle Scholar
  106. Research Units on Pediatric Psychopharmacology Autism Network. (2005). Risperidone treatment of autistic disorder: longer-term benefits and blinded discontinuation after 6 months. American Journal of Psychiatry, 162, 1361–1369.CrossRefGoogle Scholar
  107. Rimmer, J. H., Yamaki, K., Lowry, B. M., Wang, E., & Vogel, L. C. (2010). Obesity and obesity-related secondary conditions in adolescents with intellectual/developmental disabilities. Journal of Intellectual Disability Research, 54(9), 787–794.CrossRefPubMedGoogle Scholar
  108. Rincover, A., & Newsom, C. D. (1985). The relative motivational properties of sensory and edible reinforcers in teaching autistic children. Journal of Applied Behavior Analysis, 18(3), 237–248.PubMedCentralCrossRefPubMedGoogle Scholar
  109. Safer, D. J., & Zito, J. M. (2006). Treatment-emergent adverse events from selective serotonin reuptake inhibitors by age group: children versus adolescents. Journal of Child & Adolescent Psychopharmacology, 16(1–2), 159–169.CrossRefGoogle Scholar
  110. Schreck, K. A., & Williams, K. (2006). Food preferences and factors influencing food selectivity for children with autism spectrum disorders. Research in Developmental Disabilities, 27(4), 353–363.CrossRefPubMedGoogle Scholar
  111. Schreck, K. A., Williams, K., & Smith, A. F. (2004). A comparison of eating behaviors between children with and without autism. Journal of Autism and Developmental Disorders, 34(4), 433–438.CrossRefPubMedGoogle Scholar
  112. Schwimmer, J. B., Burwinkle, T. M., & Varni, J. W. (2003). Health-related quality of life of severely obese children and adolescents. The Journal of the American Medical Association, 289(14), 1813–1819.CrossRefPubMedGoogle Scholar
  113. Schwimmer, J. B., Deutsch, R., Kahen, T., Lavine, J. E., Stanley, C., & Behling, C. (2006). Prevalence of fatty liver in children and adolescents. Pediatrics, 118(4), 1388–1393.CrossRefPubMedGoogle Scholar
  114. Seiverling, L., Hendy, H. M., & Williams, K. (2011). The screening tool of feeding problems applied to children (STEP-CHILD): psychometric characteristics and associations with child and parent variables. Research in Developmental Disabilities, 32(3), 1122–1129.CrossRefPubMedGoogle Scholar
  115. Sharma, J. R., Arieff, Z., Sagar, S., & Kaur, M. (2012). Autism and obesity: prevalence, molecular basis and potential therapies. Autism Insights, 4, 1–13.Google Scholar
  116. Sharp, W. G., Jaquess, D. L., & Lukens, C. T. (2013). Multi-method assessment of feeding problems among children with autism spectrum disorders. Research in Autism Spectrum Disorders, 7(1), 56–65.CrossRefGoogle Scholar
  117. Shedlock, K., Susi, A., Gorman, G. H., Hisle-Gorman, E., Erdie-Lalena, C. R., & Nylund, C. M. (2016). Autism spectrum disorders and metabolic complications of obesity. The Journal of Pediatrics, 178, 183–187.CrossRefPubMedGoogle Scholar
  118. Shinawi, M., Sahoo, T., Maranda, B., Skinner, S. A., Skinner, C., Chinault, C., et al. (2011). 11p14. 1 microdeletions associated with ADHD, autism, developmental delay, and obesity. American Journal of Medical Genetics Part A, 155(6), 1272–1280.CrossRefGoogle Scholar
  119. Shmaya, Y., Eilat-Adar, S., Leitner, Y., Reif, S., & Gabis, L. (2015). Nutritional deficiencies and overweight prevalence among children with autism spectrum disorder. Research in Developmental Disabilities, 38, 1–6.CrossRefPubMedGoogle Scholar
  120. Silventoinen, K., Rokholm, B., Kaprio, J., & Sørensen, T. I. A. (2010). The genetic and environmental influences on childhood obesity: a systematic review of twin and adoption studies. International Journal of Obesity, 34(1), 29–40.CrossRefPubMedGoogle Scholar
  121. Simpson, C. G., Swicegood, P. R., & Gaus, M. D. (2006). Nutrition and fitness curriculum: designing instructional interventions for children with developmental disabilities. Teaching Exceptional Children, 38(6), 50–53.CrossRefGoogle Scholar
  122. Surén, P., Gunnes, N., Roth, C., Bresnahan, M., Hornig, M., Hirtz, D., & Schjølberg, S. (2014). Parental obesity and risk of autism spectrum disorder. Pediatrics, 133, 1–11.CrossRefGoogle Scholar
  123. Swinburn, B., Egger, G., & Raza, F. (1999). Dissecting obesogenic environments: The development and application of a framework for identifying and prioritizing environmental interventions for obesity. Preventive Medicine, 29(6), 563–570.CrossRefPubMedGoogle Scholar
  124. Tanofsky-Kraff, M., Yanovski, S. Z., Wilfley, D. E., Marmarosh, C., Morgan, C. M., & Yanovski, J. A. (2004). Eating-disordered behaviors, body fat, and psychopathology in overweight and normal-weight children. Journal of Consulting and Clinical Psychology, 72(1), 53–61.PubMedCentralCrossRefPubMedGoogle Scholar
  125. Tschoner, A., Engl, J., Laimer, M., Kaser, S., Rettenbacher, M., Fleischhacker, W. W., & Ebenbichler, C. F. (2007). Metabolic side effects of antipsychotic medication. International Journal of Clinical Practice, 61(8), 1356–1370.CrossRefPubMedGoogle Scholar
  126. Uddin, L. Q., & Menon, V. (2009). The anterior insula in autism: under-connected and under-examined. Neuroscience & Biobehavioral Reviews, 33(8), 1198–1203.CrossRefGoogle Scholar
  127. de Vinck-Baroody, O., Shui, A., Macklin, E. A., Hyman, S. L., Leventhal, J. M., & Weitzman, C. (2015). Overweight and obesity in a sample of children with autism spectrum disorder. Academic Pediatrics, 15(4), 396–404.CrossRefPubMedGoogle Scholar
  128. Volkow, N. D., Wang, G. J., & Baler, R. D. (2011). Reward, dopamine and the control of food intake: implications for obesity. Trends in Cognitive Sciences, 15(1), 37–46.CrossRefPubMedGoogle Scholar
  129. Wadden, T. A., Butryn, M. L., Hong, P. S., & Tsai, A. G. (2014). Behavioral treatment of obesity in patients encountered in primary care settings: a systematic review. The Journal of the American Medical Association, 312(17), 1779–1791.CrossRefPubMedGoogle Scholar
  130. Walters, R. G., Jacquemont, S., Valsesia, A., De Smith, A. J., Martinet, D., Andersson, J., Falchi, M., Chen, F., Andrieux, J., Lobbens, S., & Delobel, B. (2010). A new highly penetrant form of obesity due to deletions on chromosome 16p11. 2. Nature, 463(7281), 671–675.PubMedCentralCrossRefPubMedGoogle Scholar
  131. Wang, Y., & Lim, H. (2012). The global childhood obesity epidemic and the association between socio-economic status and childhood obesity. International Review of Psychiatry, 24(3), 176–188.PubMedCentralCrossRefPubMedGoogle Scholar
  132. Wardle, J., Carnell, S., Haworth, C. M., & Plomin, R. (2008). Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment. The American Journal of Clinical Nutrition, 87(2), 398–404.PubMedGoogle Scholar
  133. West, L., Brunssen, S. H., & Waldrop, J. (2009). Review of the evidence for treatment of children with autism with selective serotonin reuptake inhibitors. Journal for Specialists in Pediatric Nursing, 14(3), 183–191.CrossRefPubMedGoogle Scholar
  134. Whitaker, R. C., Wright, J. A., Pepe, M. S., Seidel, K. D., & Dietz, W. H. (1997). Predicting obesity in young adulthood from childhood and parental obesity. New England Journal of Medicine, 337(13), 869–873.CrossRefPubMedGoogle Scholar
  135. Xia, W., Zhou, Y., Sun, C., Wang, J., & Wu, L. (2010). A preliminary study on nutritional status and intake in Chinese children with autism. European Journal of Pediatrics, 169(10), 1201–1206.CrossRefPubMedGoogle Scholar
  136. Xiong, N., Ji, C., Li, Y., He, Z., Bo, H., & Zhao, Y. (2009). The physical status of children with autism in China. Research in Developmental Disabilities, 30(1), 70–76.CrossRefPubMedGoogle Scholar
  137. Xu, S., Han, J. C., Morales, A., Menzie, C. M., Williams, K., & Fan, Y. S. (2008). Characterization of 11p14-p12 deletion in WAGR syndrome by array CGH for identifying genes contributing to mental retardation and autism. Cytogenetic and Genome Research, 122(2), 181–187.CrossRefPubMedGoogle Scholar
  138. Yoon, Y., Wink, L. K., Pedapati, E. V., Horn, P. S., & Erickson, C. A. (2016). Weight gain effects of second-generation antipsychotic treatment in autism spectrum disorder. Journal of Child and Adolescent Psychopharmacology, 26(9), 822–827.CrossRefPubMedGoogle Scholar
  139. Young, K. M., Northern, J. J., Lister, K. M., Drummond, J. A., & O’Brien, W. H. (2007). A meta-analysis of family-behavioral weight-loss treatments for children. Clinical Psychology Review, 27(2), 240–249.CrossRefPubMedGoogle Scholar
  140. Zachor, D. A., Roberts, A. W., Hodgens, J. B., Isaacs, J. S., & Merrick, J. (2006). Effects of long-term psychostimulant medication on growth of children with ADHD. Research in Developmental Disabilities, 27(2), 162–174.CrossRefPubMedGoogle Scholar
  141. Zuckerman, K. E., Hill, A. P., Guion, K., Voltolina, L., & Fombonne, E. (2014). Overweight and obesity: Prevalence and correlates in a large clinical sample of children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(7), 1708–1719.PubMedCentralCrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Joint Doctoral Program in Clinical PsychologySan Diego State University/University of California, San DiegoSan DiegoUSA
  2. 2.Department of PediatricsUniversity of California, San DiegoLa JollaUSA
  3. 3.Department of Psychiatry and Behavioral SciencesStanford University School of MedicineStanfordUSA

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