Journal of Ultrasound

, Volume 20, Issue 4, pp 347–349 | Cite as

Image-guided thermal ablation of benign thyroid nodules

  • Claudio M. PacellaEmail author
Letter to the Editor



To clarify some relevant and significant inconsistencies and inaccuracies in review by Mainini et al. entitled “Image-guided thermal ablation of benign thyroid nodules” published in Journal of Ultrasound to avoid giving incorrect information to the reader and prevent that operators make wrong choices in the use of various devices and technologies available.


Total cases treated with radiofrequency would be 2388 and not 2435 as reported in Table 1 of this review. The major, minor complications, and side effects in the partial group treated with laser technique and reported in this review are actually 1.2, 3.8, and 35.4%, respectively. In series of patients treated with laser ablation, including a total of 2345 patients, major and minor complications are 0.7 and 1.4%, respectively. The major complications of laser technology are less severe than RFA.


Several points regarding the paper by Mainini et al. need to be discussed, and I advocate authors for replying to my considerations to clarify the issues raised.


Minimally invasive therapies Laser ablation Radiofrequency ablation Thyroid nodules 



chiarire rilevanti e significative incongruenze e inesattezze nella review di Mainini et al intitolata “Ablazione termica guidata dall’imaging dei noduli benigni tiroidei” pubblicata sul Journal of Ultrasound allo scopo di evitare di fornire informazioni non corrette a chi legge e prevenire che gli operatori facciano scelte errate nell’uso dei vari dispositivi e tecnologie disponibili.


il numero totale dei casi trattati con radiofrequenza dovrebbero essere 2.388 e non 2.435 come riportato nella tabella 1 di questa revisione. Le maggiori e le minori complicanze e gli effetti collaterali nel gruppo parziale trattato con la tecnica laser riportato in questa revisione sono in realtà rispettivamente 1,2%, 3,8% e 35,4%. Nelle serie maggiori di pazienti trattati con la ablazione laser che comprendono un totale di 2345 pazienti, le maggiori e minori complicazioni sono rispettivamente 0,7% e 1,4%. Le complicazioni maggiori della tecnologia laser sono meno severe rispetto alla ablazione con radiofrequenza.


alcuni punti che riguardano lo scritto della Mainini, e al. necessitano di essere discussi, e chiedo agli autori di rispondere alle mie considerazioni in maniera da chiarire i problemi emersi.


Compliance with ethical standards

Conflict of interest

The author is consultant to ELESTA srl Calenzano (Fi), Italy.

Ethical Approval

This article does not contain any studies with human participants performed by any of the authors.

Informed consent

For this type of study formal consent is not required.

Supplementary material

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Copyright information

© Società Italiana di Ultrasonologia in Medicina e Biologia (SIUMB) 2017

Authors and Affiliations

  1. 1.Department of Diagnostic Imaging and Interventional RadiologyRegina Apostolorum HospitalRomeItaly

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