Journal of Ultrasound

, Volume 17, Issue 2, pp 171–174 | Cite as

Herlyn Werner Wunderlich syndrome (HWWS): an unusual presentation of acute abdominal pain

  • Giulia van der BylEmail author
  • Vincenza di Giacomo
  • Vittorio Miele
Letter to the Editor

Herlyn Werner Wunderlich syndrome (HWW) is a very rare congenital malformation of the urogenital tract secondary to Müllerian developmental abnormalities MDA.

HWW syndrome results from agenesis or hypoplasia, defective vertical or lateral fusion, or resorption failure of paramesonephric ducts.

Anatomically it is characterised by a triad of didelphys uterus, obstructed hemivagina and ipsilateral renal agenesis (Fig.  1). This syndrome was described the first time on 1922 [ 1].


Endometriosis Uterine Cavity Renal Agenesis Cervical Canal Vaginal Septum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflict of interest

Giulia van der Byl, Vincenza di Giacomo, Vittorio Miele declare that they have no conflict of interest.

Informed consent

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000 (5). All patients provided written informed consent to enrolment in the study and to the inclusion in this article of information that could potentially lead to their identification.

Human and animal studies

The study was conducted in accordance with all institutional and national guidelines for the care and use of laboratory animals.


  1. 1.
    Purslow CE (1922) A case of unilateral haematocolpos, haematometra, and haematosalpinx. J Obstet Gynaecol Br Emp 29:643CrossRefGoogle Scholar
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    Troiano RN, McCarthy SM (2004) Mullerian duct anomalies: imaging and clinical issues. Radiology 233(1):19–34 (Epub 2004 Aug 18)CrossRefGoogle Scholar
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    Junqueira BL, Allen LM, Spitzer RF, Lucco KL, Babyn PS, Doria AS (2009) Müllerian duct anomalies and mimics in children and adolescents: correlative intraoperative assessment with clinical imaging1. Radiographics 29(4):1085–1103. doi: 10.1148/rg.294085737 CrossRefGoogle Scholar
  4. 4.
    Güdücü N, Gönenç G, Işçi H, Yiğiter AB, Dünder I (2012) Herlyn-Werner-Wunderlich syndrome––timely diagnosis is important to preserve fertility. J Pediatr Adolesc Gynecol 25(5):e111–e112. doi: 10.1016/j.jpag.2012.05.013 (Epub 2012 Jul 27)CrossRefGoogle Scholar

Copyright information

© Società Italiana di Ultrasonologia in Medicina e Biologia (SIUMB) 2014

Authors and Affiliations

  • Giulia van der Byl
    • 1
    Email author
  • Vincenza di Giacomo
    • 2
  • Vittorio Miele
    • 2
  1. 1.IRCCS Foundation, San Matteo Medical Center, Institute of RadiologyUniversity of PaviaPaviaItaly
  2. 2.Unità Operativa Diagnostica per Immagini nel DEA e per le UrgenzeAzienda Ospedaliera S. Camillo-ForlaniniRomeItaly

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