Is the Diet Industry Disrupting Your Microbiota?
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Purpose of Review
Gut microbes are essential to human health and dietary patterns can influence bacterial diversity and abundance, resulting in either health or disease. Here, we review if high-fat diets motivated by the diet industry can result in disruption of microbiota, which in turn leads to disease.
A high-fat diet induces microbiota dysbiosis, which is related to obesity and chronic diseases. Some mechanisms include higher bile acid secretion, which conduct its detergent effect on bacterial cell membranes, inducing the loss of non-bile-resistant species. In addition, by adopting a low-carbohydrate dietary pattern, microorganisms are deprived from short-chain fatty acids.
Evidence shows that a high-fat diet can unchain dysbiosis resulting in chronic illness and obesity.
KeywordsMicrobiota Dysbiosis Keto High-fat diet Chronic disease Intestinal integrity
body mass index
central nervous system
short-chain fatty acids
very low–carbohydrate diet
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no conflicts of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by any of the authors.
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