Current Tropical Medicine Reports

, Volume 6, Issue 4, pp 239–249 | Cite as

Current Perspectives on Maternal Influenza Immunization

  • Annette K. ReganEmail author
  • Siri E. Håberg
  • Deshayne B. Fell
Vaccines in Pregnant Women & Infants (D Schwartz and C Krubiner, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Vaccines in Pregnant Women & Infants


Purpose of Review

Pregnant women and young infants are more likely to experience severe complications associated with influenza infection and are at increased risk of hospitalization. Influenza vaccination during pregnancy produces antibodies which protect the mother against infection, and due to transplacental transfer of maternal antibodies before birth, it also protects the infant in the first few months of life.

Recent Findings

In many countries, influenza vaccination is recommended during pregnancy to protect mothers and their infants. In fact, influenza vaccine is the most widely used vaccine in pregnancy globally. When administered during pregnancy, the vaccine has been shown to be safe and effective for both mothers and their infants. Despite the health benefits, acceptance of influenza vaccine is low during pregnancy, indicating many women and infants are not protected against influenza.


Concerted efforts are needed globally to improve the proportion of women and young infants who receive the health benefits of influenza vaccination.


Influenza vaccines Influenza Maternal vaccination Pregnant women Infant health 


Funding Information

This work was partly funded by the Norwegian Research council’s Centre’s of Excellence funding scheme (#262700).

Compliance With Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.


Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Annette K. Regan
    • 1
    • 2
    Email author
  • Siri E. Håberg
    • 3
  • Deshayne B. Fell
    • 4
    • 5
  1. 1.School of Public HealthTexas A&M UniversityCollege StationUSA
  2. 2.Fielding School of Public HealthUniversity of California Los AngelesLos AngelesUSA
  3. 3.Centre for Fertility and HealthNorwegian Institute of Public HealthOsloNorway
  4. 4.School or Epidemiology and Public HealthUniversity of OttawaOttawaCanada
  5. 5.Children’s Hospital of Eastern Ontario (CHEO) Research InstituteOttawaCanada

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