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Melioidosis in Mexico: a Coordinated Effort to Educate the Medical Specialists and the Community About an Unknown Disease Endemic in the Country

  • Gerardo Alvarez-Hernandez
  • Alfredo G. TorresEmail author
Hot Topics in Tropical Medicine (ME Bottazzi and R Mejia, Section Editors)
Part of the following topical collections:
  1. Topical Collection on Hot Topics in Tropical Medicine

Abstract

Purpose of Review

Melioidosis, caused by Burkholderia pseudomallei, is virtually unknown in Mexico. The acquisition of the pathogen and development of the disease has been scarcely documented in the Mexican population, but strong evidence indicates that several of the cases are autochthonous to the country.

Recent Findings

Two fatal cases in the state of Sonora triggered a coordinated effort by the health system at the local, state, and federal level, supported by the state government, academic institutions, and international specialists, that resulted in the proper identification of the pathogen and provided strong evidence indicating that melioidosis is endemic and underreported.

Summary

In response to this coordinated effort, a Melioidosis Symposium was organized in the city of Hermosillo, Sonora, with an overall goal to educate the medical professionals and the community about the disease and to foster collaborations at the state, federal, and international level to properly identify, diagnose, and treat the next patient developing the disease.

Keywords

Burkholderia pseudomallei Melioidosis Cases Treatment Sonora Mexico 

Notes

Acknowledgments

The authors are thankful for the support of CDC, USA and INDRE, Mexico to organize this event and the logistical operation of Sonoran Secretary of Health and the University of Sonora to support all the activities associated with this symposium. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.

Compliance with Ethical Standards

Conflict of Interest

Gerardo Alvarez-Hernandez and Alfredo G. Torres declare no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

References

  1. 1.
    Dance DA. Melioidosis as an emerging global problem. Acta Trop. 2000;74:115–9.CrossRefGoogle Scholar
  2. 2.
    Wiersinga WJ, Virk HS, Torres AG, Currie BJ, Peacock SJ, Dance DAB, et al. Melioidosis. Nat Rev Dis Primers. 2018;4:17107.CrossRefGoogle Scholar
  3. 3.
    Sanchez-Villamil JI, Torres AG. Melioidosis in Mexico, Central America, and the Caribbean. Trop Med Infect Dis. 2018;3:24.Google Scholar
  4. 4.
    Rolim DB, Lima RXR, Ribeiro AKC, Colares RM, Lima LDQ, Rodríguez-Morales AJ, et al. Melioidosis in South America. Trop Med Infect Dis 2018;3:60.Google Scholar
  5. 5.
    Limmathurotsakul D, Golding N, Dance DA, Messina JP, Pigott DM, Moyes CL, et al. Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis. Nat Microbiol. 2016;1:15008.CrossRefGoogle Scholar
  6. 6.
    Wiersinga WJ, van der Poll T, White NJ, Day NP, Peacock SJ. Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei. Nat Rev Microbiol. 2006;4:272–82.CrossRefGoogle Scholar
  7. 7.
    Estes DM, Dow SW, Schweizer HP, Torres AG. Present and future therapeutic strategies for melioidosis and glanders. Expert Rev Anti-Infect Ther. 2010;8:325–38.CrossRefGoogle Scholar
  8. 8.
    Lopez Cruz G, Coronado Garcia AR, Lopez Días AV, Rodríguez Garcia J, Reyes-Gomez U, Martinez-Hernandez Y, et al. Fatal melioidosis in an oaxacan child. Int Clin Pathol J. 2019;7:18–20.Google Scholar
  9. 9.
    Boroel-Cervantes C, Ibarra-Valdez M, Miranda-Pacheco S, Sánchez-Camarena E, Wolburgth-Franco T, Ortìz-González A, et al. Melioidosis: reporte del primer caso en el estado de Sonora, México. Rev Med Inst Mex Seguro Soc. 2017;55:257–9.Google Scholar
  10. 10.
    Martínez-Hernández L, González-Híjar A, Valdéz-Vázquez R, García-López S, González-Chon O. Melioidosis: Reporte de caso y revisión de la literatura. Neumol Cir Torax. 2013;72:291–8.Google Scholar
  11. 11.
    ProMED-mail. Melioidosis - Mexico: (Sonora) suspected, fatal 2018. Available from: http://www.promedmail.org/post/6019879.
  12. 12.
    Sonora SdSPdEd. Emite Secretaría de Salud informe preliminar sobre los casos de Huásabas 2018. Available from: http://saludsonora.gob.mx/contenido/69038/emite-secretaria-de-salud-informe-preliminar-sobre-los-casos-de-huasabas.
  13. 13.
    Torres AG, Montufar FE, Gee JE, Hoffmaster AR, Elrod MG, Duarte-Valderrama C, et al. Melioidosis is in the Americas: a call to action for diagnosing and treating the disease. Am J Trop Med Hyg. 2018;99:563–4.CrossRefGoogle Scholar
  14. 14.
    Meza-Radilla G, Mendez-Canarios A, Xicohtencatl-Cortes J, Escobedo-Guerra MR, Torres AG, Ibarra JA, et al. Misidentification of Burkholderia pseudomallei and other Burkholderia species from pediatric infections in Mexico. Open Forum Infect Dis. 2019;6:ofz008.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Gerardo Alvarez-Hernandez
    • 1
    • 2
  • Alfredo G. Torres
    • 3
    Email author
  1. 1.Department of Medicine and Health SciencesUniversity of SonoraHermosilloMexico
  2. 2.Secretary of HealthHermosilloMexico
  3. 3.Department of Microbiology and ImmunologyUniversity of Texas Medical BranchGalvestonUSA

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